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363R-3

PAX-8 (SP348) Rabbit Monoclonal Antibody

Name: PAX-8 (SP348) Rabbit Monoclonal Antibody
Brand: SIGMA

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About This Item

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

SP348

Application:

ICC

Citations:

Technical Service

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Properties

biological source

rabbit blood

Quality Segment

500

conjugate

unconjugated

antibody form

IgG fraction of tissue culture supernatant

antibody product type

primary antibodies

clone

SP348

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL (concentrate (363R-34-RUO) Research Use Only), vial of 0.1 mL
(concentrate (363R-34)), vial of 0.5 mL (concentrate (363R-35)), vial of 1.0 mL (concentrate (363R-36)), vial of 1.0 mL (concentrate (363R-36-RUO) Research Use Only), vial of 1.0 mL (pre-dilute (363R-37-RUO) Research Use Only), vial of 1.0 mL (pre-dilute ready-to-use (363R-37)), vial of 25.0 mL (pre-dilute ready-to-use (363R-30)), vial of 25.0 mL (pre-dilute ready-to-use (363R-30-RUO)), vial of 7.0 mL (pre-dilute ready-to-use (363R-38)), vial of 7.0 mL (pre-dilute ready-to-use (363R-38-RUO) Research Use Only)

manufacturer/tradename

Cell Marque^®

technique(s)

immunocytochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:10-1:20 (concentrated))

isotype

IgG

control

ovarian carcinoma, papillary carcinoma of thyroid, renal cell carcinoma, (Fallopian Tube)

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Description

General description

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in neoplastic transformation of some epithelial cell types of these mature tissues.1 It can be useful for marking several types of carcinoma including, but not limited to, ovarian serous carcinoma, clear cell renal cell carcinoma and papillary thyroid carcinoma. Certain anti-PAX-8 antibodies may react with lymphocytes and their neoplasms, which has been attributed to cross-reactivity with PAX-5 due to sequence homology between PAX-8 and PAX-5, but clone SP348 does not exhibit reactivity in these cell types.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c