Key Documents

View All Documentation

36799

7-(Diethylamino)coumarin-3-carboxylic acid

Name: 7-(Diethylamino)coumarin-3-carboxylic acid
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥98.0% (HPCE)

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₅NO₄

CAS Number:

50995-74-9

Molecular Weight:

261.27

UNSPSC Code:

12352106

NACRES:

NA.32

PubChem Substance ID:

57649663

MDL number:

MFCD00068721

Beilstein/REAXYS Number:

6145963

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

product line

BioReagent

Quality Level

200

assay

≥98.0% (HPCE)

mp

222-224 °C (dec.) (lit.)

solubility

DMF: soluble, DMSO: soluble

fluorescence

λ_ex 409 nm; λ_em 473 nm in 0.1 M Tris pH 9.0

suitability

suitable for fluorescence

SMILES string

CCN(CC)c1ccc2C=C(C(O)=O)C(=O)Oc2c1

InChI

1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)

InChI key

WHCPTFFIERCDSB-UHFFFAOYSA-N

Application

7-(Diethylamino)coumarin-3-carboxylic acid (7-DCCA) may be used to study its photophysical properties in various solvents and solvent mixtures and as a fluorescent label for amine modification and protein conjugation

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Fluorescent label for amine modification and protein conjugation

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Photophysical properties of 7-(diethylamino)coumarin-3-carboxylic acid in the nanocage of cyclodextrins and in different solvents and solvent mixtures.

Aninda Chatterjee et al.

Photochemistry and photobiology, 89(2), 280-293 (2012-09-26)

The photophysical properties of 7-(diethylamino) coumarin-3-carboxylic acid (7-DCCA) were studied in cyclodextrins (α, β, γ,-CDs), different neat solvents and solvent mixtures by using steady state absorption, emission and time-resolved fluorescence spectroscopy. We have observed that with gradual increase in concentration

Driving force of binding of amyloid beta-protein to lipid bilayers.

Keisuke Ikeda et al.

Biochemical and biophysical research communications, 370(3), 525-529 (2008-04-09)

Amyloid beta-protein (Abeta) has been reported to interact with a variety of lipid species, although the thermodynamic driving force remains unclear. We investigated the binding of Abetas labeled with the dye diethylaminocoumarin (DAC-Abetas) to lipid bilayers under various conditions. DAC-Abeta-(1-40)

Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid.

Atsuko Kakio et al.

Biochemistry, 41(23), 7385-7390 (2002-06-05)

GM1 ganglioside-bound amyloid beta-protein (GM1-Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) plaques, has been suggested to accelerate amyloid fibril formation by acting as a seed. We have previously found using dye-labeled Abeta that Abeta recognizes

Design of irreversible optical nanothermometers for thermal ablations.

Tiffany P Gustafson et al.

Chemical communications (Cambridge, England), 49(7), 680-682 (2012-12-12)

Nanothermometers composed from a gold nanorod core, temperature sensitive linker and fluorescent dye are reported. The nanothermometers have low fluorescence due to a self-quenching mechanism at temperatures below 50 °C and become highly fluorescence above 70 °C.

Recombinant Chromosome 7 Driven by Maternal Chromosome 7 Pericentric Inversion in a Girl with Features of Silver-Russell Syndrome.

Ilaria Catusi et al.

International journal of molecular sciences, 21(22) (2020-11-15)

Maternal uniparental disomy of chromosome 7 is present in 5-10% of patients with Silver-Russell syndrome (SRS), and duplication of 7p including GRB10 (Growth Factor Receptor-Bound Protein 10), an imprinted gene that affects pre-and postnatal growth retardation, has been associated with

View All Related Papers

Articles

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

Global Trade Item Number

SKU	GTIN
36799-100MG-F	04061833277126

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service