Key Documents

View All Documentation

37291

Dihydroethidium

Name: Dihydroethidium
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥95% (HPCE)

Synonym(s):

2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine, Hydroethidine

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₁N₃

CAS Number:

104821-25-2

Molecular Weight:

315.41

UNSPSC Code:

12161505

NACRES:

NA.32

PubChem Substance ID:

57649715

MDL number:

MFCD00077335

Beilstein/REAXYS Number:

5107482

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

product line

BioReagent

Quality Level

100

assay

≥95% (HPCE)

form

solid

mol wt

315.41 g/mol

solubility

acetonitrile: soluble, methanol: soluble

fluorescence

λ_ex 358 nm; λ_em 461 nm, λ_ex 392 nm; λ_em 410 nm in methanol

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CCN1C(c2ccccc2)c3cc(N)ccc3-c4ccc(N)cc14

InChI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

InChI key

XYJODUBPWNZLML-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Clinical & Diagnostics

Dry Dyes & Certified Stains

Tissue Diagnostics

Application

Dihydroethidium (dHEt), a fluorescene probe, is used to detect the presence of reactive oxygen species (ROS) such as superoxides.

Redox indicator. Blue fluorescence until oxidized to ethidium.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

B-ring reduced analog of ethidium

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Microbial biofilm proliferation within sealer-root dentin interfaces is affected by sealer type and aging period.

Karina A Roth et al.

Journal of endodontics, 38(9), 1253-1256 (2012-08-16)

Root canal fillings are intended to prevent microbial proliferation over time in the canal after treatment. The objective of this study was to assess biofilm proliferation within the sealer-dentin interfaces of 2 methacrylate resin-based systems, self-etch (SE) and total-etch (TE)

Methylene blue inhibits the asexual development of vivax malaria parasites from a region of increasing chloroquine resistance.

Rossarin Suwanarusk et al.

The Journal of antimicrobial chemotherapy, 70(1), 124-129 (2014-08-26)

Methylene blue, once discarded due to its unsettling yet mild side effects, has now found a renewed place in the pharmacopoeia of modern medicine. The continued spread of drug-resistant Plasmodium vivax and Plasmodium falciparum has also led to a recent

Noise-induced hearing loss (NIHL) as a target of oxidative stress-mediated damage: cochlear and cortical responses after an increase in antioxidant defense.

Anna Rita Fetoni et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(9), 4011-4023 (2013-03-01)

This study addresses the relationship between cochlear oxidative damage and auditory cortical injury in a rat model of repeated noise exposure. To test the effect of increased antioxidant defenses, a water-soluble coenzyme Q10 analog (Qter) was used. We analyzed auditory

Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products.

Francisco R M Laurindo et al.

Methods in enzymology, 441, 237-260 (2008-06-17)

Assessment of low-level superoxide in nonphagocytic cells is crucial for assessing redox-dependent signaling pathways and the role of enzymes such as the NADPH oxidase complex. However, most superoxide probes present inherent limitations. Particularly, assessment of dihydroethidium (DHE) fluorescence is limited

ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production.

Hai-Yan Jin et al.

PloS one, 7(6), e38502-e38502 (2012-06-14)

Inflammation and oxidative stress play a crucial role in angiotensin (Ang) II-mediated vascular injury. Angiotensin-converting enzyme 2 (ACE2) has recently been identified as a specific Ang II-degrading enzyme but its role in vascular biology remains elusive. We hypothesized that loss

View All Related Papers

Global Trade Item Number

SKU	GTIN
8530570100	04027269098254
15382-25G	04061838741141
15382-5G	04061832593715
15382-100G	04061832593708
8530570025	04027269098247
37291-25MG	04061831834352
37291-100MG	04061833488911

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service