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382M-1

SOX-11 (MRQ-58) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-58, monoclonal
Application:
IHC (p)
Citations:
10
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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-58, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (382M-14), vial of 0.5 mL concentrate (382M-15), bottle of 1.0 mL predilute (382M-17), vial of 1.0 mL concentrate (382M-16), bottle of 7.0 mL predilute (382M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1

control

mantle cell lymphoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... SOX11(6664)

Related Categories

General description

SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination. citation Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
SOX-11 Positive Control Slides, Product No. 382S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000499407
0000499407
0000499409
0000499409
0000499406

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Bernd Weigle et al.
Oncology reports, 13(1), 139-144 (2004-12-08)
Malignant glioma comprises the majority of primary human brain tumors with 16,800 new cases reported each year in the USA. Its prognosis remains dismal despite numerous attempts to improve conventional therapeutic modalities. Therefore, much effort is devoted to the exploration
Tiemo Katzenberger et al.
British journal of haematology, 142(4), 538-550 (2008-06-20)
Mantle cell lymphoma (MCL) is an aggressive lymphoid tumour characterized by the translocation t(11;14)(q13;q32) and a poor clinical outcome (median survival: 3-4 years). Recent studies revealed that increased proliferation of the tumour cells and certain chromosomal aberrations, such as deletions
Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives.
Itziar Salaverria et al.
Haematologica, 91(1), 11-16 (2006-01-26)
M Hargrave et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 210(2), 79-86 (1997-10-23)
Sry, the mammalian Y-linked testis determining gene, is a member of a family of genes known as Sox genes, which encode transcription factors related by a DNA-binding motif termed the HMG box. Sox genes are known to have diverse roles
Kai Fu et al.
Blood, 106(13), 4315-4321 (2005-08-27)
Cyclin D1 overexpression is believed to be essential in the pathogenesis of mantle cell lymphoma (MCL). Hence, the existence of cyclin D1-negative MCL has been controversial and difficult to substantiate. Our previous gene expression profiling study identified several cases that
View All Related Papers

Global Trade Item Number

SKUGTIN
382M-180841683140023
382M-140841683121688
382M-160841683121701
382M-170841683121718
382M-16-RUO04061836534196
382M-150841683121695

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