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385M-1

SALL4 (6E3) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6E3, monoclonal
Application:
IHC (p)
Citations:
3
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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

6E3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (385M-14), vial of 0.5 mL concentrate (385M-15), bottle of 1.0 mL predilute (385M-17), vial of 1.0 mL concentrate (385M-16), bottle of 7.0 mL predilute (385M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1

control

dysgerminoma, seminoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... SALL4(57167)

Related Categories

General description

Sal-like protein 4 (SALL4) is a zinc-finger transcription factor that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors, and teratomas. SALL4 expression is also seen in the spermatogonia of the normal testis.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000509162
0000509162
0000497572
0000497573
0000497573

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Dengfeng Cao et al.
The American journal of surgical pathology, 33(7), 1065-1077 (2009-04-25)
The diagnosis of testicular germ cell tumors (GCTs) sometimes can be challenging without ancillary markers. Here we performed an immunohistochemical study of a novel stem cell marker SALL4 in a large series of 110 primary testicular GCTs (65 pure and
Dengfeng Cao et al.
The American journal of surgical pathology, 33(6), 894-904 (2009-03-20)
Ovarian primitive germ cell tumors (GCTs) are uncommon tumors and sometimes pose diagnostic challenges. Among them, yolk sac tumor (YST) poses the greatest diagnostic difficulty and can be mistaken for clear cell carcinoma (CCC). Current immunohistochemical markers such as alpha-fetoprotein
Wei Cui et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(12), 1585-1592 (2006-09-26)
SALL4, a newly identified zinc-finger transcriptional factor important for embryonic development, is mapped to chromosome 20q13. Previously, we reported that SALL4 was constitutively expressed in acute myeloid leukemia and SALL4 transgenic mice developed acute myeloid leukemia. In this study, we

Global Trade Item Number

SKUGTIN
385M-180841683140214
385M-150841683140184
385M-140841683140177
385M-160841683140191
385M-16-RUO04061836546809
385M-170841683140207

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