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Merck
CN

386R-1

MyoD1 (EP212) Rabbit Monoclonal Primary Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP212, monoclonal
Application:
IHC (p)
Citations:
2
Technical Service
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP212, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (386R-14), vial of 0.5 mL concentrate (386R-15), bottle of 1.0 mL predilute (386R-17), vial of 1.0 mL concentrate (386R-16), bottle of 7.0 mL predilute (386R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG

control

rhabdomyosarcoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... MYOD1(4654)

General description

MyoD1, one of the MyoD family of myogenic helix-loop-helix transcription factors, combinedwith myogenin, plays a role in coordinating the differentiation of skeletal muscle. MyoD1 isexpressed in myoblasts before differentiation. Anti-MyoD1 immunostaining identifies cellscommitted to myogenesis in their earliest phase. In conjunction with other markers, antiMyoD1 may be used for the identification of rhabdomyosarcoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
MyoD1 Positive Control Slides, Product No. 386S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Regulatory Information

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N J Sebire et al.
Journal of clinical pathology, 56(6), 412-416 (2003-06-05)
The diagnosis of paediatric solid tumours is often based on small tissue needle biopsies in which many different entities demonstrate a "small round cell tumour" phenotype and in which there may be insufficient tissue to allow the interpretation of diagnostic
Raffaella A Morotti et al.
The American journal of surgical pathology, 30(8), 962-968 (2006-07-25)
Immunohistochemistry remains the current ancillary method of choice in the pathologic evaluation of small blue round-cell tumors. In at least 20% of cases of rhabdomyosarcoma (RMS), it is considered an essential factor in the final and/or differential diagnosis of the



Global Trade Item Number

SKUGTIN
386R-16-RUO04061836568412
386R-170841683121794
386R-180841683121800
386R-140841683121763
386R-160841683121787
386R-150841683121770