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39294

Fluo 3-AM solution

Name: Fluo 3-AM solution
Brand: SIGMA

1 mM in DMSO, ≥99.0% (TLC)

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About This Item

Empirical Formula (Hill Notation):

C₅₁H₅₀Cl₂N₂O₂₃

CAS Number:

121714-22-5

Molecular Weight:

1129.85

MDL number:

MFCD00083336

UNSPSC Code:

12171500

NACRES:

NA.32

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Quality Level

100

assay

≥99.0% (TLC)

form

liquid

concentration

1 mM in DMSO

fluorescence

λ_ex 506 nm; λ_em 525.0 nm±5.0 nm in 0.1 M Tris pH 8.0, esterase

storage temp.

−20°C

SMILES string

Clc1[c](cc2[o]c3c(c(c2c1)c4cc(c(cc4)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOc5c(ccc(c5)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)cc(c(c3)OCOC(=O)C)Cl)=O

InChI

1S/C51H50Cl2N2O23/c1-28-7-9-39(54(19-47(62)74-24-69-30(3)57)20-48(63)75-25-70-31(4)58)45(13-28)66-11-12-67-46-14-34(8-10-40(46)55(21-49(64)76-26-71-32(5)59)22-50(65)77-27-72-33(6)60)51-35-15-37(52)41(61)17-42(35)78-43-18-44(38(53)16-36(43)51)73-23-68-29(2

InChI key

PTPUOMXKXCCSEN-UHFFFAOYSA-N

Related Categories

Detection Substrates & Enzymes

Proteins & Enzymes

General description

Cell permeable fluorescent indicator of intracellular Ca²⁺; non-fluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca²⁺; lower binding affinity allows measurement of higher peaks of Ca²⁺ transients than with Fura 2.

Application

suitable as fluorescent Ca sensitive probe (after cleavage of the AM ester)

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F

flash_point_c

87 °C

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Magnetotherapy has been receiving increased attention as an attractive strategy for modulating cell physiology directly at the site of injury, thereby providing the medical community with a safe and non-invasive therapy. Yet, how magnetic field influences tendon cells both at

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Methylglyoxal (MGO), an endogenous reactive carbonyl compound, plays a key role in the pathogenesis of diabetic neuropathy. The aim of this study is to investigate the role of MGO in diabetic itch and hypoalgesia, two common symptoms associated with diabetic

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Global Trade Item Number

SKU	GTIN
39294-1ML	04061831981766

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