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Merck
CN

406RA-05A

Human Osteoblasts-Rheumatoid Arthritis: HOb-RA, adult

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About This Item

UNSPSC Code:
41106514
Biological source:
human bone (rheumatoid arthritic)
Growth mode:
Adherent
Morphology:
osteoblast
Relevant disease(s):
arthritis
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biological source

human bone (rheumatoid arthritic)

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 46

morphology

osteoblast

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

arthritis

shipped in

dry ice

storage temp.

−196°C

General description

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Human Osteoblasts-Rheumatoid Arthritis, HOb-RA, are isolated from bone of patients with rheumatoid arthritis (RA) and provide an excellent model system to study the patophisiology of that disease in vitro, including matrix mineralization, effects of inflammatory mediators and bone morphogenic proteins, physiological control of bone remodeling and regulation of bone metabolism.Characterization: Positive for bone mineralization.

Application

model system to study the pathophisiology of rheumatoid arthritis, matrix mineralization, effects of inflammatory mediators, bone morphogenic proteins, bone remodeling and metabolism

Biochem/physiol Actions

Bone

Preparation Note

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

Please refer to the HOb-RA Culture Protocol.

Other Notes

Basal Medium containing 10% FBS & 10% DMSO


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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