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Merck
CN

42052

cis-11-Methyl-2-dodecenoic acid

≥90.0% (HPLC)

Synonym(s):

DSF, Diffusible signal factor

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About This Item

Empirical Formula (Hill Notation):
C13H24O2
CAS Number:
Molecular Weight:
212.33
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
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Product Name

cis-11-Methyl-2-dodecenoic acid, ≥90.0% (HPLC)

InChI

1S/C13H24O2/c1-12(2)10-8-6-4-3-5-7-9-11-13(14)15/h9,11-12H,3-8,10H2,1-2H3,(H,14,15)/b11-9-

SMILES string

CC(C)CCCCCCC\C=C/C(O)=O

InChI key

SNTXNGAQYNSTHI-LUAWRHEFSA-N

assay

≥90.0% (HPLC)

storage temp.

−20°C

Quality Level

Application

Diffusible signal factor (cis-11-methyl-2-dodecenoic acid, DSF) is used to study cell-cell communication by pathogenic bacteria such as Xanthomonas campestris pv. Campestris (Xcc). DSF is involved in the synchronization of virulence gene expression and biofilm dispersal.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ben E Clifton et al.
Nature chemical biology, 14(6), 542-547 (2018-04-25)
The emergence of enzymes through the neofunctionalization of noncatalytic proteins is ultimately responsible for the extraordinary range of biological catalysts observed in nature. Although the evolution of some enzymes from binding proteins can be inferred by homology, we have a
Yaping Yang et al.
Scanning, 38(6), 825-836 (2016-06-30)
Disulfiram (DSF) has been proved to have broad-spectrum anti-alcoholism effects, and it is also found to show stronger anti-tumor effects after chelating with Cu2+ to form DSF-Cu complex. In this work, we studied the anti-tumor activity of DSF-Cu in MCF-7
Abeer A Ageeli et al.
Nucleic acids research, 47(3), 1468-1481 (2018-11-22)
Nucleic acid triplexes may regulate many important biological processes. Persistent accumulation of the oncogenic 7-kb long noncoding RNA MALAT1 is dependent on an unusually long intramolecular triple helix. This triplex structure is positioned within a conserved ENE (element for nuclear
Anita Sarkar et al.
Nature communications, 9(1), 1956-1956 (2018-05-18)
Furin cleavage of the HIV envelope glycoprotein is an essential step for cell entry that enables formation of well-folded, native-like glycosylated trimers, releases constraints on the fusion peptide, and limits enzymatic processing of the N-glycan shield. Here, we show that
Olubukayo-Opeyemi Oyetayo et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 97, 151-157 (2016-11-21)
Solvents used for therapeutic proteins in downstream processing and in formulations often contain stabilizing additives that inhibit denaturation and aggregation. Such additives are mostly selected based on their positive effect on thermal stability of the protein, and are often derived

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