42418
D-Lactaldehyde solution
≥95.0% (TLC), liquid
Synonym(s):
(2R)-2-Hydroxypropanal solution, (R)-2-Hydroxypropionaldehyde solution
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About This Item
Empirical Formula (Hill Notation):
C3H6O2
CAS Number:
Molecular Weight:
74.08
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
Product Name
D-Lactaldehyde solution, 1 M in H2O
SMILES string
C[C@@H](O)C([H])=O
InChI
1S/C3H6O2/c1-3(5)2-4/h2-3,5H,1H3/t3-/m1/s1
InChI key
BSABBBMNWQWLLU-GSVOUGTGSA-N
assay
≥95.0% (TLC)
form
liquid
optical purity
enantiomeric ratio: ≥98.0:2.0 (HPLC)
concentration
1 M in H2O
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
D-Lactaldehyde is an intermediate in the pyruvate metabolic pathway. Pyruvaldehyde is irreversibly produced from D-lactaldehyde via the enzyme glyoxylate reductase.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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D-Fucose metabolism in a pseudomonad. IV. Cleavage of 2-keto-3-deoxy-D-fuconate to pyruvate and D-lactaldehyde by 2-keto-3-deoxy-L-arabonate aldolase.
A S Dahms et al.
The Journal of biological chemistry, 247(7), 2238-2241 (1972-04-10)
P J Thornalley
Amino acids, 6(1), 15-23 (1994-02-01)
The formation of the reactiveα,β-dicarbonyl metabolite, methylglyoxal, is increased during hyperglycaemia associated with diabetes mellitus. Methylglyoxal is metabolised to S-D-lactoylglutathione and D-lactate by the glyoxalase system and to hydroxyacetone (95%) and D-lactaldehyde by aldose reductase. Methylglyoxal and hydroxyacetone bind and
THE METABOLISM OF LACTALDEHYDE. VII. THE OXIDATION OF D-LACTALDEHYDE IN RAT LIVER.
S M TING et al.
Biochimica et biophysica acta, 97, 407-415 (1965-03-08)
D L Vander Jagt et al.
The Journal of biological chemistry, 267(7), 4364-4369 (1992-03-05)
The substrate specificities of human aldose reductase and aldehyde reductase toward trioses, triose phosphates, and related three-carbon aldehydes and ketones were evaluated. Both enzymes are able to catalyze the NADPH-dependent reduction of all of the substrates used. Aldose reductase shows
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