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Merck
CN

42867

Dextran sulfate sodium salt

Mr ~40,000

Synonym(s):

DSS Dextran Sulfate Sodium

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About This Item

NACRES:
NA.25
UNSPSC Code:
12352201
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form

powder

Quality Segment

mol wt

Mr ~40,000

technique(s)

tissue culture: suitable

loss

≤10% loss on drying

color

white to off-white

useful pH range

6.0-8 (10 g/L)

mp

(Decomposes on heating.)

solubility

water: soluble

suitability

suitable for component for culture media

storage temp.

room temp

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
42867-5G04061832104942
42867-25G04061832104935
42867-100G04061835541331