44001
N-Acetyl-D-glucosamine 6-sulfate sodium salt
≥98.0% (TLC)
Synonym(s):
GlcNAc-6S
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About This Item
Linear Formula:
C8H14NO9SNa
CAS Number:
Molecular Weight:
323.25
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
biological source
synthetic
Quality Level
description
Mixed anomers
assay
≥98.0% (TLC)
form
solid
optical activity
[α]20/D 32.0±2.0, c = 0.1% (w/v) in water
technique(s)
thin layer chromatography (TLC): suitable
color
colorless
storage temp.
−20°C
SMILES string
[Na+].CC(=O)N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@@H]1O
InChI
1S/C8H15NO9S.Na/c1-3(10)9-5-7(12)6(11)4(18-8(5)13)2-17-19(14,15)16;/h4-8,11-13H,2H2,1H3,(H,9,10)(H,14,15,16);/q;+1/p-1/t4-,5-,6-,7-,8?;/m1./s1
InChI key
CBUJZKTVEFVBBG-FROKLYQUSA-M
Application
N-Acetyl-D-glucosamine 6-sulfate (GlcNAc-6S) is used as a substrate and inhibitor to identify, differentiate and characterize various sulfatase(s), especially N-acetylglucosamine-6-sulphatase(s).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
N H Elçioglu et al.
Genetic counseling (Geneva, Switzerland), 20(2), 133-139 (2009-08-05)
A novel loss-of-function mutation in the GNS gene causes Sanfilippo syndrome type D: Mucopolysaccharidosis type IIID (MIM 252940) is the least common form of the four subtypes of Sanfilippo syndrome. It is an autosomal recessive lysosomal disorder caused by a
Andrea Mok et al.
Genomics, 81(1), 1-5 (2003-02-08)
Mucopolysaccharidosis type IIID (MPS IIID; Sanfilippo syndrome type D; MIM 252940) is caused by deficiency of the activity of N-acetylglucosamine-6-sulfatase (GNS), which is normally required for degradation of heparan sulfate. The clinical features of MPS IIID include progressive neurodegeneration, with
Shengyuan Xu et al.
The Biochemical journal, 387(Pt 3), 841-847 (2004-12-15)
A 75 kDa protein was purified to homogeneity from granule extracts of normal human granulocytes using Sephadex G-75 chromatography, Mono-S cation exchange chromatography and chromatofocusing. The protein consisted of one chain with a molecular mass of 75 kDa, as determined
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 44001-25MG | 04061832385013 |