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Merck
CN

46943

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Empirical Formula (Hill Notation):
C44H56O7
CAS Number:
7308-90-9
Molecular Weight:
696.91
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
57650888
EC Number:
230-764-2
Beilstein/REAXYS Number:
6034843
MDL number:
MFCD00038409

Key Documents

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InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

Quality Level

100

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Related Categories

Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM1418
BCCH7419
BCCG4884
BCCD0504
BCBX4865

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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
J E Domínguez-Muñoz et al.
Clinical chemistry, 44(4), 869-875 (1998-05-15)
The serum pancreolauryl test has limited sensitivity for detecting mild pancreatic insufficiency. The aim of this study was to optimize the serum pancreolauryl test so as to increase the probability of positive results in patients with chronic pancreatitis. The study
I A Murray et al.
Postgraduate medical journal, 79(934), 471-473 (2003-09-05)
To audit the specificity and value of the pancreolauryl test (PLT) for the diagnosis of pancreatic insufficiency. A retrospective case note review of 47 patients who had a PLT during three consecutive years. A 650 bedded district general hospital. Patient
M Fuchs et al.
Zentralblatt fur Chirurgie, 120(6), 472-477 (1995-01-01)
In a follow up study 19 patients after Billroth-I, 22 patients after Billroth-II-resection and 38 patients after total gastrectomy (23 with Roux-Y-reconstruction and 15 with Longmire-Gütgemann) underwent a stool fat determination and an indirect pancreatic function test with fluorescein dilaurate
L M Burrell et al.
Scandinavian journal of clinical and laboratory investigation, 51(8), 675-680 (1991-12-01)
We have employed an oral test of pancreatic digestive function using fluorescein dilaurate (a substrate for pancreatic cholesterol ester hydrolase), administered together with pancreatic enzyme supplements, in order to test the hypothesis that urinary excretion of fluorescein provides a simple
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