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50839

Catalpol

≥96% (HPLC)

Synonym(s):

(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside, Catalpinoside, De(p-hydroxybenzoyl)catalposide

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About This Item

Empirical Formula (Hill Notation):
C15H22O10
CAS Number:
2415-24-9
Molecular Weight:
362.33
NACRES:
NA.25
PubChem Substance ID:
329757639
UNSPSC Code:
12352211
EC Number:
219-324-0
MDL number:
MFCD11111524
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Quality Level

100

assay

≥96% (HPLC)

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(CO)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1

InChI key

LHDWRKICQLTVDL-PZYDOOQISA-N

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Biochem/physiol Actions

The primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF4176V
BCCH6295
BCCF1851
BCBX4606
BCBV4769

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Analysis of catalpol derivatives by characteristic neutral losses using liquid chromatography combined with electrospray ionization multistage and time-of-flight mass spectrometry.
Jun-Li Hong et al.
Rapid communications in mass spectrometry : RCM, 24(17), 2680-2686 (2010-08-27)
Yu-Min Liu et al.
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 9(7), 783-788 (2011-07-14)
To observe the effects of sera containing Liuwei Dihuang Pill (LDP), a compound traditional Chinese herbal medicine, and its monomer catalpol on transforming growth factor-β1 (TGF-β1)/Smad pathway in HK-2 cells. Wistar rats were intragastrically administered with LDP twice daily for
Hui-Feng Zhu et al.
International journal of biological sciences, 6(5), 443-453 (2010-09-10)
To investigate the role and mechanism of catalpol in brain angiogenesis in a rat model of stroke, the effect of catalpol (5 mg/kg; i.p) or vehicle administered 24 hours after permanent middle cerebral artery occlusion (pMCAO) on behavior, angiogenesis, ultra-structural
Cheng-Fang Wang et al.
Brain research, 1307, 158-165 (2009-10-27)
Diabetes mellitus can cause dysfunction of the central nervous system called "diabetic encephalopathy." Although insulin and various oral drugs are used to treat diabetes, they do not completely prevent the development of diabetic encephalopathy, and novel strategies for the prevention
Jing Bi et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 543-550 (2012-11-21)
A large body of evidence suggests that the inflammatory reaction plays an important role in the pathogenesis of neurodegenerative diseases. Our previous studies described the neuroprotective effects of catalpol in lipopolysaccharide (LPS)-induced inflammatory models, in which catalpol was shown to
View All Related Papers

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Global Trade Item Number

SKUGTIN
50839-25MG04061832404509

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