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Merck
CN

51290

Hemoglobin from bovine blood

lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder

Synonym(s):

Bovine hemoglobin, Hb, Methemoglobin

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About This Item

CAS Number:
UNSPSC Code:
12352202
MDL number:
eCl@ss:
42030116
Form:
powder
Assay:
≥90% (SDS-PAGE)
Biological source:
bovine blood
Mol wt:
Mr ~64500
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biological source

bovine blood

Quality Segment

assay

≥90% (SDS-PAGE)

form

powder

quality

2×cryst., lyophilized

mol wt

Mr ~64500

technique(s)

UV/Vis spectroscopy: suitable

impurities

salt, none detected, ~0.3% Fe

loss

≤8% loss on drying

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

General description

Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.

Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter, NO scavenger
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Other Notes

Review: Oxygen carrier proteins
Sales restrictions may apply

Disclaimer

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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