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Merck
CN

52131

2-C-Methyl-D-erythritol 4-phosphate lithium salt

≥98% (TLC)

Synonym(s):

MEP

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About This Item

Empirical Formula (Hill Notation):
C5H11O7P · xLi+
CAS Number:
Molecular Weight:
214.11 (free acid basis)
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
Assay:
≥98% (TLC)
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Quality Segment

assay

≥98% (TLC)

storage temp.

−20°C

SMILES string

O=P(O)(O)OC[C@H](O)[C@@](O)(C)CO.C

InChI

1S/C5H13O7P/c1-5(8,3-6)4(7)2-12-13(9,10)11/h4,6-8H,2-3H2,1H3,(H2,9,10,11)/t4-,5+/m1/s1

InChI key

XMWHRVNVKDKBRG-UHNVWZDZSA-N

Application

2-C-Methyl-D-erythritol 4-phosphate (MEP), the product of reductoisomerase IspC and first committed MEP pathway intermediate, is used to study the non-mevalonate MEP pathway for the biosynthesis of isoprenoids. MEP is used as a precursor for the synthesis of 4-diphosphocytidyl-2-C-methyl D-erythritol (CDP-ME), a key intermediate of the non-mevalonate pathway.

Biochem/physiol Actions

Metabolite intermediate specific to the non-mevalonate MEP pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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