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Merck
CN

53557

FITC–DEAE–Dextran

average mol wt 3,000-6,000

Synonym(s):

FITC–DEAE–Dextran 4, Fluorescein isothiocyanate–Diethylaminoethyl–Dextran

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352116

Key Documents

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Product Name

FITC–DEAE–Dextran, average mol wt 3,000-6,000

form

solid

mol wt

average mol wt 3,000-6,000

composition

nitrogen content, 2-5%

extent of labeling

0.001-0.020 mol/mol FITC glucose

fluorescence

λex 493 nm; λem 518 nm in 0.1 M Tris pH 8.0

Quality Level

100

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Application

FITC-DEAE-Dextran 4 is a cationic fluorescent dextran that may be used to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-DEAE-Dextran 4 may be use to compare selectivity versus neutral FITC-Dextran 4 or anionic FITC-CM-Dextran 4.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ4611
BCCG4522
BCCD0844
BCBZ4508
BCBV5800

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J K Leypoldt et al.
Kidney international, 43(4), 837-844 (1993-04-01)
The influence of molecular charge on macromolecule transport during peritoneal dialysis was assessed by determining transperitoneal transport rates for fluorescent-labeled macromolecules (molecular radii from 15 to 40 A) that differed only in molecular charge: neutral dextran, anionic dextran sulfate and
Carrier and dose effects on the pharmacokinetics of T-0128, a camptothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats.
Harada M, Murata J, Sakamura Y, et al.
J. Controlled Release, 71, 71-86 (2001)
Reduced diffusion of charge-modified, conformationally intact anionic Ficoll relative to neutral Ficoll across the rat glomerular filtration barrier in vivo.
Axelsson J, Sverrisson K, Rippe A, et al.
American Journal of Physiology: Renal Physiology, 301, F708-F712 (2011)

Articles

FITC-labelled polysaccharides

Explore FITC-labelled polysaccharides and their properties, including impact of molecular weight on molecule dimensions.

FITC标记多糖

包括FITC-葡聚糖、FITC-DEAE-葡聚糖(FDD)、FITC-羧甲基 - 葡聚糖（FCM-葡聚糖）在内的FITC标记多糖的补充信息。本页面主要介绍了重均分子量对于对应分子尺寸和其他物理性质的影响

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