53796
(Z-)-4-Bromo-5-(bromomethylene)-2(5H)-furanone
≥97.0% (GC)
Synonym(s):
Furanone C-30
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About This Item
Empirical Formula (Hill Notation):
C5H2Br2O2
CAS Number:
Molecular Weight:
253.88
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
120928
Product Name
(Z-)-4-Bromo-5-(bromomethylene)-2(5H)-furanone, ≥97.0% (GC)
InChI
1S/C5H2Br2O2/c6-2-4-3(7)1-5(8)9-4/h1-2H/b4-2-
SMILES string
Br\C=C1/OC(=O)C=C1Br
InChI key
DPGLBHQUHFJRJS-RQOWECAXSA-N
assay
≥97.0% (GC)
97.0-103.0% (T)
form
solid
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
The synthetic furanones C30 interfered with the actions of acyl-HSL molecules and inhibited gene expression regulated by quorum-sensing systems in P. aeruginosa.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Jingming Zhao et al.
The Indian journal of medical research, 147(4), 400-406 (2018-07-13)
Pseudomonas aeruginosa is an opportunistic pathogen that can cause nosocomial bloodstream infections in humans. This study was aimed to explore the association of furanone C-30 with biofilm formation, quorum sensing (QS) system and antibiotic resistance in P. aeruginosa. An in
Young Mok Heo et al.
Marine drugs, 16(12) (2018-12-19)
In our previous study, all Arthrinium isolates from Sargassum sp. showed high bioactivities, but studies on marine Arthrinium spp. are insufficient. In this study, a phylogenetic analysis of 28 Arthrinium isolates from seaweeds and egg masses of Arctoscopus japonicus was
J Fernando Montes García et al.
Antonie van Leeuwenhoek, 113(9), 1371-1383 (2020-07-17)
Actinobacillus seminis is an autochthonous gram-negative bacterium that affects reproductive organs, causing epididymitis, low fertility, and occasional abortions in ovine and goats. The virulence factors and the pathogenicity mechanisms of A. seminis have not been clearly elucidated yet. In this
B X V Quecan et al.
Frontiers in microbiology, 10, 867-867 (2019-05-21)
Quorum sensing (QS) regulates bacterial gene expression and studies suggest quercetin, a flavonol found in onion, as a QS inhibitor. There are no studies showing the anti-QS activity of plants containing quercetin in its native glycosylated forms. This study aimed
Kulwadee Karnjana et al.
Fish & shellfish immunology, 88, 91-101 (2019-03-01)
Bacteria respond to host immunity for their proliferation and survival by cell-cell communications such as biofilm formation, bioluminescence, and secreting virulence factors. In the biofilm form, bacteria are more resistant to various antimicrobial treatments and withstand the host's immune system.
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