55222
6-Carboxytetramethylrhodamine
BioReagent, suitable for fluorescence, ≥90% (HPLC)
Synonym(s):
6-TAMRA
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About This Item
Empirical Formula (Hill Notation):
C25H22N2O5
CAS Number:
Molecular Weight:
430.45
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
description
single isomer
product line
BioReagent
assay
≥90% (HPLC)
form
solid
solubility
DMSO: soluble, methanol: soluble
fluorescence
λex 543 nm; λem 575 nm in 0.1 M Tris pH 8.0
suitability
suitable for fluorescence
SMILES string
CN(C)c1ccc2c(OC3=C\C(C=CC3=C2c4cc(ccc4C([O-])=O)C(O)=O)=[N+](\C)C)c1
InChI
1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)
InChI key
COCMHKNAGZHBDZ-UHFFFAOYSA-N
Application
6-Carboxytetramethylrhodamine (6-TAMRA) is used to create fluorescent DNA probes and labeled proteins/peptides. The corresponding succinimidyl ester is a single isomer fluorophore most commonly used in automated DNA sequencing.
The corresponding succinimidyl ester is a single isomer fluorophore most commonly used in automated DNA sequencing.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Patrick A Marcotte et al.
Analytical biochemistry, 332(1), 90-99 (2004-08-11)
A novel fluorescent substrate was devised for the sirtuin (SIRT) class of human protein deacetylases comprised of a peptide sequence containing a single acetyl-lysine residue, with a fluorescent group (tetramethylrhodamine-6-carboxylic acid, 6-TAMRA) near the carboxyl terminus and a nonfluorescent quenching
Yutaka Ueno et al.
Micromachines, 11(9) (2020-09-16)
This study introduces a modeling method for a supermolecular structure of microtubules for the development of a force generation material using motor proteins. 3D imaging by confocal laser scanning microscopy (CLSM) was used to obtain 3D volume density data. The
Miguel Tavares Pereira et al.
Frontiers in veterinary science, 7, 625921-625921 (2021-02-27)
In the dog, implantation takes place at approximately 17 days of embryonal life and, while exposed to relatively high circulating progesterone concentrations, embryos presence is required for the formation of decidua. Furthermore, a balance between pro- and anti-inflammatory responses in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M103-10MG | 04061832091785 |
| 55222-50MG-F | 04061832532578 |
| 55222-10MG-F | 04061832532561 |