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55496

Hydroxyapatite

Name: Hydroxyapatite
Brand: SIGMA

′high resolution′

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:

3Ca₃(PO₄)₂ · Ca(OH)₂

CAS Number:

1306-06-5

Molecular Weight:

502.31

UNSPSC Code:

12352200

PubChem Substance ID:

57651499

EC Number:

215-145-7

MDL number:

MFCD00010904

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capacity

≥1.2 mg/g, dry material binding capacity (DNA), ≥15 mg/g, dry material binding capacity (BSA)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Other Notes

DNA purification; Analysis of DNA damage; Stabilization of double-standard DNA

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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A hydroxylapatite batch assay for quantitation of cellular DNA damage.

P M Kanter et al.

Analytical biochemistry, 97(1), 77-84 (1979-08-01)

Rapid isolation of mouse DNA from cells in tissue culture.

W Meinke et al.

Analytical biochemistry, 58(1), 82-88 (1974-03-01)

The nucleic acid-hydroxylapatite interaction. I. Stabilization of native double-stranded deoxyribonucleic acid by hydroxylapatite.

H G Martinson

Biochemistry, 12(1), 139-145 (1973-01-02)

Lower reoperation rate for cemented hemiarthroplasty than for uncemented hemiarthroplasty and internal fixation following femoral neck fracture: 12- to 19-year follow-up of patients aged 75 years or more.

Bjarke Viberg et al.

Acta orthopaedica, 84(3), 254-259 (2013-04-19)

Elderly patients with displaced femoral neck fractures are commonly treated with a hemiarthroplasty (HA), but little is known about the long-term failure of this treatment. We compared reoperation rates for patients aged at least 75 years with displaced femoral neck

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques.

Sophie E P New et al.

Circulation research, 113(1), 72-77 (2013-04-26)

We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute

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Global Trade Item Number

SKU	GTIN
CRM90128-50MG	04065265917919
45515-250MG	04061832340883

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