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Merck
CN

60188

Potassium dichromate

BioUltra, ≥99.5% (RT)

Synonym(s):

Potassium bichromate

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About This Item

Linear Formula:
K2Cr2O7
CAS Number:
Molecular Weight:
294.18
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
231-906-6
MDL number:
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product line

BioUltra

assay

≥99.5% (RT)

impurities

insoluble matter, passes filter test

loss

≤0.05% loss on drying, 110 °C

pH

3.5-5.0 (25 °C, 0.1 M in H2O)

mp

398 °C (lit.)

solubility

H2O: 0.1 M at 20 °C, clear, orange

anion traces

chloride (Cl-): ≤10 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤20 mg/kg, Cd: ≤10 mg/kg, Co: ≤20 mg/kg, Cu: ≤10 mg/kg, Fe: ≤20 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤20 mg/kg, Pb: ≤50 mg/kg, Sr: ≤50 mg/kg, Zn: ≤10 mg/kg

absorption

no transmittance (UV) in H2O at 0.1 M

SMILES string

[K+].[K+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

1S/2Cr.2K.7O/q;;2*+1;;;;;;2*-1

InChI key

KMUONIBRACKNSN-UHFFFAOYSA-N

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Application

Potassium bichromate may be used to induce acute renal failure (ARF) that mimics occupational hazards. It may be used to study the mechanism and affects of chromium induced renal failure and rescue methodologies.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Muta. 1B - Ox. Sol. 2 - Repr. 1B - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

target_organs

Cardio-vascular system, Respiratory system

Storage Class

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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N Susa et al.
Archives of toxicology, 71(6), 345-350 (1997-01-01)
Incubation of primary cultures of rat hepatocytes with K2CR2O7 and deferoxamine (DFO), an iron chelator, resulted in a marked decrease in cellular levels of DNA single-strand breaks caused by K2Cr2O7. Cellular treatment with DFO also suppressed both dichromate-induced cytotoxicity--evaluated by
Amrit Pal Singh et al.
Pharmacological reports : PR, 64(1), 31-44 (2012-05-15)
The animal models are pivotal for understanding the characteristics of acute renal failure (ARF) and development of effective therapy for its optimal management. Since the etiology for induction of renal failure is multifold, therefore, a large number of animal models
Shafaqat Ali et al.
Environmental toxicology and chemistry, 32(10), 2234-2239 (2013-06-19)
A hydroponic experiment was carried out to examine the effect of hydrogen sulfide (H2 S) in alleviating chromium (Cr) stress in barley. A 2-factorial design with 6 replications was selected, including 3 levels of NaHS (0 μM, 100 μM, and
Bour-Jr Wang et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 110(12), 775-779 (2012-01-18)
Occupational dermatitis among cement workers is a major occupational health concern. The two most important occupational hazards for cement workers are irritant and allergic cement contact dermatitis. The objective of this study was to investigate the severity of occupational cement
Fu-Jun Liu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 110(2), 307-318 (2009-06-03)
Werner syndrome is a premature aging disorder characterized by cancer predisposition that is caused by loss of the Werner syndrome protein (WRN) helicase/exonuclease DNA repair protein. Hexavalent chromium is an environmental carcinogen and genotoxicant that is associated with respiratory cancers

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