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Merck
CN

61760

Lectin from Canavalia ensiformis

lyophilized, ≥50% (GE), powder

Synonym(s):

Agglutinin from jack beans, Con A

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.56
MDL number:
Form:
powder
Biological source:
Canavalia ensiformis
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biological source

Canavalia ensiformis

form

powder

quality

lyophilized

Quality Level

concentration

≥50% (GE)

technique(s)

XRF: suitable

storage temp.

2-8°C

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料
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Lectins in the isolation of receptors on lymphocytes.
J J Marchalonis
Methods in enzymology, 150, 463-477 (1987-01-01)
H. Bittiger and H.P. Schnebli, eds.
Concanavalin A as a Tool, 639-639 (1976)
Dongxu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 144, 111576-111576 (2020-08-05)
Plant-derived dietary lectins have been reported to be involved in the pathogenesis of several inflammatory diseases, including hepatitis, inflammatory bowel disease, diabetes, and celiac disease. In this present study, we aimed to assess whether green tea polyphenols (GTPs) exerts protective

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