62962
L-α-Lysophosphatidylcholine
egg yolk, ≥99.0% (TLC)
Synonym(s):
3-sn-Lysophosphatidylcholine, L-α-Lysolecithin
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About This Item
biological source
egg yolk
description
zwitterionic
assay
≥99.0% (TLC)
form
powder or solid
composition
16:0, ~69% , 18:0, ~27% , 18:1, ~3%
solubility
chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
wet ice
storage temp.
−20°C
Application
- The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).
- Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).
Biochem/physiol Actions
3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .
Other Notes
Preparation of demembranated frog sperm chromatin
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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