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Merck
CN

68152

Atto 580 Q maleimide

BioReagent, suitable for fluorescence

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Technical Service
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product line

BioReagent

assay

≥90% (coupling to thiols)

form

solid

manufacturer/tradename

ATTO-TEC GmbH

technique(s)

UV/Vis spectroscopy: suitable

suitability

suitable for fluorescence, corresponds for UV test

storage temp.

−20°C

Application

Atto 580Q is a new quencher for fluorescence characterized by high molecular absorption (110.000). Atto 580Q is characterized by a high photostability and thermostability. It is moderately hydrophilic, and soluble in polar solvents as DMF or DMSO. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Global Trade Item Number

SKUGTIN
68152-1MG-F04061823355032