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68903

4-Methylumbelliferyl β-D-galactopyranoside-6-sulfate sodium salt

galactose-6-sulfate sulphatase substrate, ≥90% (HPLC), powder

Synonym(s):

4-MU-Gal-6S sodium salt, 4-Methylumbelliferyl Beta-D-galactopyranoside-6-sulfate sodium salt, 4-Methylumbelliferyl Gal-6S sodium salt

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About This Item

Empirical Formula (Hill Notation):
C16H17NaO11S
CAS Number:
126938-14-5
Molecular Weight:
440.35
UNSPSC Code:
12352204
PubChem Substance ID:
329761212
NACRES:
NA.32
MDL number:
MFCD01861961
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Product Name

4-Methylumbelliferyl β-D-galactopyranoside-6-sulfate sodium salt, ≥90% (HPLC)

Quality Level

100

assay

≥90% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](COS([O-])(=O)=O)[C@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O11S.Na/c1-7-4-12(17)26-10-5-8(2-3-9(7)10)25-16-15(20)14(19)13(18)11(27-16)6-24-28(21,22)23;/h2-5,11,13-16,18-20H,6H2,1H3,(H,21,22,23);/q;+1/p-1/t11-,13+,14+,15-,16-;/m1./s1

InChI key

KHTOBGQRIASILC-XNSOHGFJSA-M

Application

suitable as a fluorogenic substrate for galactose-6-sulfate sulphatase; fluorogenic substrate for the diagnosis of Morquio disease type A

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3329
BCCM2778
BCCJ3444
BCCJ4947
BCCD2845

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O P van Diggelen et al.
Clinica chimica acta; international journal of clinical chemistry, 187(2), 131-139 (1990-02-28)
4-Methylumbelliferyl-beta-D-galactopyranoside-6-sulphate was synthesized and used for the determination of galactose-6-sulphate sulphatase activity. Fibroblasts and leucocytes from 12 different Morquio A patients, showed 0.0-2.7% of mean normal galactose-6-sulphate sulphatase activity. Heterozygotes showed intermediate activities. The enzymatic liberation of the fluorochrome from
H Zhao et al.
Prenatal diagnosis, 10(2), 85-91 (1990-02-01)
A new fluorogenic substrate, 4 methylumbelliferyl beta-D-6-sulphogalactoside, was used for the assay of galactose-6-sulphate sulphatase activity in chorionic villi, cultured villus cells, and amniocytes. The fluorometric assay is much more convenient than the conventional assay using radiolabelled, sulphated oligosaccharides. Both

Global Trade Item Number

SKUGTIN
68903-5MG04061832764832