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69293

Sucralose

≥98.0% (HPLC)

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
329761543
EC Number:
259-952-2
Beilstein/REAXYS Number:
3654410
MDL number:
MFCD03648615
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Quality Level

200

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]/D 86.0±2.0°, c = 1 in H2O

sweetness

600 × sucrose

color

white to off-white

useful pH range

6-8 (20 °C, 100 g/L)

mp

114.5  °C ((238.1 °F ) - OECD Test Guideline 102)

solubility

~300 g/L at 25 °C (77 °F)

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

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Application

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide
Sucralose is a non-caloric sugar used as a sweetener that activates T1R2/T1R3 sweet taste receptors and modulates glucagon-like peptide-1, glucose-dependent insulinotrophic peptide, and incretin secretion.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF8350V
BCCN7504
0000487388
0000487388
WXBF5824V

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Nimesh Shukla et al.
Archives of biochemistry and biophysics, 639, 38-43 (2017-12-31)
Sucralose is a commonly employed artificial sweetener that appears to destabilize protein native structures. This is in direct contrast to the bio-preservative nature of its natural counterpart, sucrose, which enhances the stability of biomolecules against environmental stress. We have further
Christopher B Forsyth et al.
PloS one, 6(12), e28032-e28032 (2011-12-07)
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves
Ann-Kristin Eriksson Wiklund et al.
Chemosphere, 86(1), 50-55 (2011-10-01)
The non-calorie sweetener sucralose - sucrose containing three chlorine atoms - is intensively sweet and has become a popular substitute for sugar. Its widespread use, exceptional stability in combination with high water solubility have thus resulted in contamination of recipient
Virender K Sharma et al.
Chemosphere, 87(6), 644-648 (2012-02-22)
The kinetics of the oxidation of sucralose, an emerging contaminant, and related monosaccharides and disaccharides by ferrate(VI) (Fe(VI)) were studied as a function of pH (6.5-10.1) at 25°C. Reducing sugars (glucose, fructose, and maltose) reacted faster with Fe(VI) than did
Ana I Domingos et al.
Nature neuroscience, 14(12), 1562-1568 (2011-11-15)
We developed an assay for quantifying the reward value of nutrient and used it to analyze the effects of metabolic state and leptin. In this assay, mice chose between two sippers, one of which dispensed water and was coupled to
View All Related Papers

Global Trade Item Number

SKUGTIN
504746000104055977244090
I6138-50MG04061832091525
I6138-100MG04061832091518
69293-100G04061832768755

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