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Merck
CN

71790

Sodium nucleinate

Synonym(s):

Ribonucleic acid sodium salt

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.25
MDL number:
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form

powder

loss

~5% loss on drying, 20 °C (HV)

solubility

H2O: 0.1 g/mL, clear to turbid, brown-yellow (hot)

storage temp.

2-8°C

Quality Level

General description

Sodium nucleinate is a derivative of tetrahydrophthalazine.

Application

<ul>
<li><strong>Tetrahydrophthalazine derivative &quot;sodium nucleinate&quot; exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>

Biochem/physiol Actions

Sodium nucleinate (SN) serves as an immunomodulatory substance, that possess anti-inflammatory effects.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品
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Tetrahydrophthalazine Derivative
Jukic T, et al.
Collegium Antropologicum, 36(2), 409-412 (2012)

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