73156
N-Methyl-L-serine
≥98% (TLC)
Synonym(s):
(S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
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About This Item
Empirical Formula (Hill Notation):
C4H9NO3
CAS Number:
Molecular Weight:
119.12
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2498641
Quality Segment
assay
≥98% (TLC)
form
powder
optical activity
[α]/D +9.5±1.0°, c = 1 in 1 M HCl
composition
carbon, 39.5-41.1% , nitrogen, 11.5-12.0%
color
white
mp
204 °C
SMILES string
CN[C@@H](CO)C(O)=O
InChI
1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
InChI key
PSFABYLDRXJYID-VKHMYHEASA-N
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts.
N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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