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Merck
CN

75574

Hyaluronic acid sodium salt from Streptococcus equi

mol wt 500,000-750,000

Synonym(s):

Sodium hyaluronate

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About This Item

CAS Number:
9067-32-7
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
MFCD01773053

Key Documents

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Product Name

Hyaluronic acid sodium salt from Streptococcus equi, mol wt 500,000-750,000

SMILES string

[Na+].N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(=O)O)O)CO)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3O)CO)O)NC(=O)C)C(=O)O)C(=O)C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI key

YWIVKILSMZOHHF-QJZPQSOGSA-N

biological source

(Streptococcus equi)

form

powder

mol wt

500,000-750,000

color

white

solubility

water: ~5 g/L

suitability

conforms to structure for Infrared spectrum

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

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Related Categories

Application

suitable as substrate for hyaluronidase

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ9988
BCBM2885V
BCBM2885

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Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting.
Shen, Y.I., et al.
Biomaterials Science (2014)
L Y W Bourguignon et al.
Oncogene, 31(2), 149-160 (2011-06-21)
MicroRNAs are often associated with the pathogenesis of many cancers, including head and neck squamous cell carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to have a critical role in tumor cell survival, chemoresistance and HNSCC progression. In this study, we
Jason A Burdick et al.
Advanced materials (Deerfield Beach, Fla.), 23(12), H41-H56 (2011-03-12)
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human body, is crucial for many cellular and tissue functions and has been in clinical use for over thirty years. When chemically modified, HA can be transformed into many
Xiao Tian et al.
Nature, 499(7458), 346-349 (2013-06-21)
The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole rat. In
David D Waddell et al.
The journal of knee surgery, 27(2), 99-104 (2013-07-23)
Osteoarthritic (OA) knee pain can be successfully treated with hylan G-F 20 (Synvisc, Sanofi Biosurgery, Cambridge, MA) with few local adverse events. However, a few studies have identified hyaluronate positive (HA+) granulomas in the synovial tissue of patients treated with
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