76157
(4R)-4-Hydroxy-L-glutamic acid
≥98.0% (TLC)
Synonym(s):
erythro-(4R)-4-Hydroxy-L-glutamic acid, H-(2S,4R)-γ-Hydroxy-Glu-OH
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About This Item
Empirical Formula (Hill Notation):
C5H9NO5
CAS Number:
Molecular Weight:
163.13
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Beilstein/REAXYS Number:
1725871
Product Name
(4R)-4-Hydroxy-L-glutamic acid, ≥98.0% (TLC)
Quality Segment
assay
≥98.0% (TLC)
form
powder
optical activity
[α]/D 20.5±1.5°, c = 1 in H2O
color
white
mp
171 °C
storage temp.
−20°C
SMILES string
N[C@@H](C[C@@H](O)C(O)=O)C(O)=O
InChI
1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1
InChI key
HBDWQSHEVMSFGY-STHAYSLISA-N
Biochem/physiol Actions
(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner.
Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 76157-10MG | 04061832720258 |
| 76157-50MG | 04061832720265 |