76258
Paraplast Plus®
suitable for electron microscopy, pellets (fast-melting)
Synonym(s):
Paraplast Plus® embedding media, Paraffin – polyisobutylene mixture
form
pellets (fast-melting)
Quality Level
technique(s)
electron microscopy: suitable
thickness
≤1 μm , short ribbons
≤2 μm , sectioning: continuous ribbons
mp
56-57 °C
application(s)
hematology
histology
storage temp.
2-8°C
General description
Paraplast Plus® is a refined mixture of highly purified paraffin containing complex elastomer of regulated molecular weights plus a small percentage of dimethyl sulfoxide (DMSO) for fast tissue penetration. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.
Application
Paraffin polyisobutylene mixture is a tissue embedding medium composed of highly purified paraffin and polyisobutylene and a low level of dimethyl sulfoxide (DMSO) to enhance the rate of tissue penetration. Paraffin-polyisobutylene (76258) supports thin wrinkle-free sectioning down to 4 microM with more flexible and continuous ribbons.
Recommended for large specimens and tissue that commonly presents infiltration problems.
Features and Benefits
- Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
- 0.8% DMSO enhances ease of infiltration and sectioning for tissues difficult to process with regular Paraplast.
- Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
- Optimal infiltration and embedding for high-quality sections.
- Great compression resistance and ribbon continuity.
- Remarkable morphology preservation and distortion-free sections.
Legal Information
Paraplast is a registered trademark of Leica Biosystems
Paraplast Plus is a registered trademark of Leica Biosystems
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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