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Merck
CN

77161

Pepsin from porcine gastric mucosa

tested according to Ph. Eur.

Synonym(s):

Pepsini pulvis, Pepsin A, Pepsin from hog stomach

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About This Item

CAS Number:
9001-75-6
UNSPSC Code:
12352204
eCl@ss:
42010127
EC Number:
232-629-3
NACRES:
NA.54
MDL number:
MFCD00081840
EC Number:
3.4.23.1 (BRENDA, IUBMB)

Key Documents

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Product Name

Pepsin from porcine gastric mucosa, tested according to Ph. Eur.

agency

USP/NF
tested according to Ph. Eur.

form

powder

mol wt

35 kDa

UniProt accession no.

P00791

storage temp.

2-8°C

Gene Information

pig ... LOC396892(396892)

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Analysis Note

Optimum pH is 2-4. Active in 4 M urea and 3 M guanidine HCl. Stable at 60 °C. Pepsin is irreversibly inactivated at pH 8.0 - 8.5.

Application

Pepsin cleavage can be used to produce F(ab′)2 fragments of antibodies. pepsin at www.sigma-aldrich.com/enzymeexplorer.

Biochem/physiol Actions

Preferential cleavage: hydrophobic and aromatic residues in P1 and P1′ postitions. Cleaves Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe and Phe-Tyr bonds in the β chain of insulin

Disclaimer

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

动植物源性产品
低风险生物材料
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4822
BCCH8258
BCCG7567
BCCF8814
BCCC7833

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