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Merck
CN

78493

Atto 610

BioReagent, suitable for fluorescence, ≥90% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C25H31ClN2O6
Molecular Weight:
490.98
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
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product line

BioReagent

assay

≥90% (HPLC)

form

powder

manufacturer/tradename

ATTO-TEC GmbH

λ

in ethanol (with 0.1% trifluoroacetic acid)

UV absorption

λ: 614-620 nm Amax

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

[O-]Cl(=O)(=O)=O.C\[N+](C)=C1/C=CC2=Cc3cc4CCCN(CCCC(O)=O)c4cc3C(C)(C)C2=C1

InChI

1S/C25H30N2O2.ClHO4/c1-25(2)21-15-20(26(3)4)10-9-17(21)13-19-14-18-7-5-11-27(12-6-8-24(28)29)23(18)16-22(19)25;2-1(3,4)5/h9-10,13-16H,5-8,11-12H2,1-4H3;(H,2,3,4,5)

InChI key

SLQQGEVQWLDVDF-UHFFFAOYSA-N

Application

Atto labels are designed for highest sensitivity applications. A unique combination of advantages makes them highly favorable tools for all kinds of labeling applications. And some of their properties make them specifically interesting for single molecule detection. Atto labels are based on rigid structures and do not show any cis-trans-isomerization, which lowers brightness of signals and leads to environment dependency, e.g., spectral shifts by conjugation.
Atto 610 shows an molar extinction of 110,000 and QY of 70% in water (70% in ethanol). Decay time is 3.3 ns.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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A simple and effective protocol for detections of protein-protein and protein-small molecule interactions has been developed. After interactions between proteins and their corresponding ligands, we employed colloidal silver staining for producing active substrates for surface-enhanced Raman scattering (SERS) and surface-enhanced
Lu Liu et al.
Biochemistry, 45(36), 10865-10872 (2006-09-07)
Serpins regulate serine proteases by forming metastable covalent complexes with their targets. The protease docks with the serpin and cleaves the serpin's reactive center loop (RCL) forming an acylenzyme intermediate. Cleavage triggers insertion of the RCL into beta sheet A



Global Trade Item Number

SKUGTIN
N8002-5G04061834118329
N3020-100ML04061834115687
60700-25G04061835521029
229113-5G04061835345649
7602-804061839407107
60700-5G04061832676500
78493-1MG-F04061823356640