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Merck
CN

78544

Glucose tetrasaccharide

≥99.0% (TLC)

Synonym(s):

Glcα1-6Glcα1-4Glcα1-4Glc

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About This Item

Empirical Formula (Hill Notation):
C24H42O21
CAS Number:
Molecular Weight:
666.58
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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Quality Level

assay

≥99.0% (TLC)

form

powder

color

white

suitability

corresponds for LC-MS

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)C(O)O[C@@H]4CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-10(29)12(31)17(36)23(43-8)45-20-7(3-27)42-24(18(37)14(20)33)44-19-6(2-26)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21?,22+,23-,24-/m1/s1

InChI key

FPBCRLIOSBQLHS-QVTSYAGHSA-N

Application

Glucose tetrasaccharide (Glc4) is used as a reference in analysis of urinary glucose tetrasacchaide, a biomarker for Pompe disease and other glycogen storage diseases.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Chihiro Yonee et al.
Brain & development, 34(10), 834-839 (2012-04-24)
Pompe disease is an autosomal recessive disorder caused by deficiency of the lysosomal enzyme, acid alpha-glucosidase (GAA). To the best of our knowledge, no studies have reported the results of systematic and sequential CT analyses before and during ERT. In
Unique oligosaccharide (apparently glucotetrasaccharide) in urine of patients with glycogen storage diseases.
K Oberholzer et al.
Clinical chemistry, 36(7), 1381-1381 (1990-07-01)
D A Zopf et al.
Journal of immunological methods, 48(1), 109-119 (1982-01-01)
A radioimmunoassay is described that allows rapid determination of a urinary oligosaccharide -- Glc alpha 1-6Glc alpha 1-4Glc alpha 1-4Glc [(Glc)4] -- at concentrations greater than 2 pmol/microliter. Antibodies produced in rabbits immunized with the phenethylamine derivative of (Glc)4 coupled
A Lundblad et al.
Journal of immunological methods, 68(1-2), 217-226 (1984-03-30)
Monoclonal antibodies were produced in BALB/cJ mice against a urinary glucose-containing tetrasaccharide (Glc)4 coupled to keyhole limpet hemocyanin (KLH). The immune response was studied using 7 different strains of mice and 11 different immunization protocols. From 6 fusions using the
Yan An et al.
Molecular genetics and metabolism, 85(4), 247-254 (2005-05-12)
A tetraglucose oligomer, Glcalpha1-6Glcalpha1-4Glcalpha1-4Glc, designated Glc4, has been shown to be a putative biomarker for the diagnosis of Pompe disease. The purpose of this study was to assess whether Glc4 could be used to monitor the therapeutic response to recombinant

Global Trade Item Number

SKUGTIN
78544-1MG04061826054536

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