81333
Poly-L-lysine hydrobromide
mol wt 20,000-30,000
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About This Item
form
fibers
mol wt
20,000-30,000
storage temp.
−20°C
SMILES string
Cl.NCCCCC(N)C(O)=O
InChI
1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1
InChI key
WBSCNDJQPKSPII-KKUMJFAQSA-N
Biochem/physiol Actions
Poly-L-lysine hydrobromide is used in the construction of biocompatible nanocapsules and for positively charged NH2 group modification of bioactive surfaces in applications such as microarray and micropattern assembly.
Other Notes
Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Disclaimer
Sterile solutions are stable for up to 2 years when stored at 2-8°C. It should be stored desiccated at -20°C.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Javeed Shaikh Mohammed et al.
Langmuir : the ACS journal of surfaces and colloids, 22(6), 2738-2746 (2006-03-08)
Micropatterns of different biomaterials with micro- and nanoscale features and defined spatial arrangement on a single substrate are useful tools for studying cellular-level interactions, and recent reports have highlighted the strong influence of scaffold compliance in determining cell behavior. In
M G Katsikogianni et al.
Journal of materials science. Materials in medicine, 21(3), 963-968 (2010-01-02)
Staphylococcus epidermidis adhesion onto materials with specific chemical functionalities, under flow, was investigated by using surfaces prepared by self-assembly of alkyl silane monolayers on glass. Terminal methyl (CH(3)) and amino (NH(2)) groups were formed by chemical vapor deposition of silanes
Sergey Rozhok et al.
Langmuir : the ACS journal of surfaces and colloids, 22(26), 11251-11254 (2006-12-13)
Construction of biomotors is an exciting area of scientific research that holds great promise for the development of new technologies with broad potential applications in areas such as the energy industry and medicine. Herein, we demonstrate the fabrication of prealigned