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818M-9

Cytokeratin 8 & 18 (B22.1 & B23.1) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
B22.1 & B23.1, monoclonal
Application:
IHC (p)
Citations:
3
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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

diluted ascites fluid

antibody product type

primary antibodies

clone

B22.1 & B23.1, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (818M-94), vial of 0.5 mL concentrate (818M-95), bottle of 1.0 mL predilute (818M-97), vial of 1.0 mL concentrate (818M-96), bottle of 7.0 mL predilute (818M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

prostate, salivary gland

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT8(3856)

Related Categories

General description

Cytokeratins 8 &18 (CK 8 & 18) are major components of the intermediate filaments in the thyroid, liver, and most simple epithelia (e.g. breast, gastrointestinal and respiratory tracts). Anti-CK 8 & 18 is found to stain most adenocarcinomas and squamous cell carcinomas. CK8 & 18 are frequently used as the epithelial markers for identifying Paget cells, metastatic gastric, and colorectal carcinomas.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

Cytokeratin 8 & 18 Positive Control Slides, Product No. 818S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000524690
0000524690
0000515365
0000515365
0000486334

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J M Corson
Pathology annual, 21 Pt 2, 47-81 (1986-01-01)
Keratin protein immunohistochemistry is a powerful diagnostic tool whose role has already been firmly established in many surgical pathology laboratories. Recent studies of the biology of keratin proteins have defined the heterogeneity of keratin protein expression among various epithelial tissues
B Angus et al.
The Journal of pathology, 153(4), 377-384 (1987-12-01)
Production of a new monoclonal antibody designated NCL-5D3 is described. The antibody recognizes several low molecular weight cytokeratins, in particular cytokeratin Moll number 8 as determined by immunoblotting studies, and is highly effective for immunocytochemistry using routinely processed paraffin-embedded material.
M Sasaki et al.
Histopathology, 32(3), 199-208 (1998-05-06)
Recent reports suggest that genetic examination of K-ras or p53 mutation is more sensitive for the detection of occult lymph node metastasis in colorectal carcinomas than conventional examination by haematoxylin and eosin (H & E) staining or immunohistochemistry for gene

Global Trade Item Number

SKUGTIN
818M-960841683144755
818M-970841683144762
818M-940841683144731
818M-96-RUO04061836552404
818M-980841683144779
818M-950841683144748

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