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Merck
CN

82553

Pterine-6-carboxylic acid

≥98.0% (HPLC)

Synonym(s):

2-Amino-4-hydroxypteridine-6-carboxylicacid

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About This Item

Empirical Formula (Hill Notation):
C7H5N5O3
CAS Number:
Molecular Weight:
207.15
UNSPSC Code:
12352106
NACRES:
NA.79
PubChem Substance ID:
EC Number:
213-435-8
Beilstein/REAXYS Number:
227689
MDL number:
Assay:
≥98.0% (HPLC)
Form:
powder or crystals
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InChI key

QABAUCFGPWONOG-UHFFFAOYSA-N

InChI

1S/C7H5N5O3/c8-7-11-4-3(5(13)12-7)10-2(1-9-4)6(14)15/h1H,(H,14,15)(H3,8,9,11,12,13)

SMILES string

NC1=Nc2ncc(nc2C(=O)N1)C(O)=O

biological source

synthetic

assay

≥98.0% (HPLC)

form

powder or crystals

color

white to faint yellow

storage temp.

2-8°C

Quality Level

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Other Notes

Review: Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Tal Offer et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(9), 2101-2107 (2007-03-08)
The known functions of folate are to support one-carbon metabolism and to serve as photoreceptors for cryptochromes and photolyases. We demonstrate that 5-methyltetrahydrofolate (5-MTHF, the predominant folate in plasma) is also a potent, near diffusion limited, scavenger of singlet oxygen
M J Akhtar et al.
Journal of pharmaceutical and biomedical analysis, 23(6), 1039-1044 (2000-11-30)
A study of the photolysis of folic acid in aqueous solution by visible radiation in the presence of riboflavin has been made. The second-order rate constants for the bimolecular interaction of folic acid and riboflavin have been determined in the
Ilja Gasan Osojnik Črnivec et al.
Food & function, 11(2), 1467-1477 (2020-01-25)
Encapsulation provides efficient approaches to increase stability and delivery of poorly soluble bioactive components, predominantly for fortification of beverages and similar liquid-based foods. In this study, folic acid was encapsulated within conventional and emulsion-templated alginate-pectin hydrogels, proliposomes, and a combination
Kazutaka Hirakawa et al.
Archives of biochemistry and biophysics, 410(2), 261-268 (2003-02-08)
DNA damage mediated by photosensitizers participates in solar carcinogenesis. Fluorescence measurement and high-performance liquid chromatography analysis demonstrated that photoirradiated folic acid, one of the photosensitizers in cells, generates pterine-6-carboxylic acid (PCA). Experiments using 32P-labeled DNA fragments obtained from a human
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
C A Nichol et al.
Annual review of biochemistry, 54, 729-764 (1985-01-01)

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