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83697

Rhodamine 6G

Name: Rhodamine 6G
Brand: SIGMA

suitable for fluorescence, BioReagent

Synonym(s):

Basic Red 1

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About This Item

Linear Formula:

C₂₈H₃₁N₂O₃Cl

CAS Number:

989-38-8

Molecular Weight:

479.01

EC Number:

213-584-9

UNSPSC Code:

12171500

NACRES:

NA.32

PubChem Substance ID:

57652965

MDL number:

MFCD00012665

Beilstein/REAXYS Number:

3900071

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product line

BioReagent

Quality Level

200

form

powder

solubility

H₂O: soluble, ethanol: soluble

fluorescence

λ_ex 528 nm; λ_em 551 nm in methanol

suitability

suitable for fluorescence

SMILES string

Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC

InChI

1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;

InChI key

VYXSBFYARXAAKO-WTKGSRSZSA-N

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Related Categories

Clinical & Diagnostics

Dry Dyes & Certified Stains

Tissue Diagnostics

Application

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

Biochem/physiol Actions

A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.

Analysis Note

λmax. ∼530 nm, E(1%/1cm) ∼2000-2300 (96% Ethanol)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Stalled cerebral capillary blood flow in mouse models of essential thrombocythemia and polycythemia vera revealed by in vivo two-photon imaging.

T P Santisakultarm et al.

Journal of thrombosis and haemostasis : JTH, 12(12), 2120-2130 (2014-09-30)

Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPNs) that share the JAK2(V617F) mutation in hematopoietic stem cells, leading to excessive production of predominantly platelets in ET, and predominantly red blood cells (RBCs) in PV. The major cause

Molecular photobleaching kinetics of Rhodamine 6G by one- and two-photon induced confocal fluorescence microscopy.

Christian Eggeling et al.

Chemphyschem : a European journal of chemical physics and physical chemistry, 6(5), 791-804 (2005-05-11)

Under high-excitation irradiance conditions in one- and two-photon induced fluorescence microscopy, the photostability of fluorescent dyes is of crucial importance for the detection sensitivity of single molecules and for the contrast in fluorescence imaging. Herein, we report on the dependence

Spatial distribution and mobility of the Ran GTPase in live interphase cells.

Asmahan Abu-Arish et al.

Biophysical journal, 97(8), 2164-2178 (2009-10-22)

The GTPase Ran is a key regulator of molecular transport through nuclear pore complex (NPC) channels. To analyze the role of Ran in its nuclear transport function, we used several quantitative fluorescence techniques to follow the distribution and dynamics of

Internal-Modified Dithiol DNA-Directed Au Nanoassemblies: Geometrically Controlled Self-Assembly and Quantitative Surface-Enhanced Raman Scattering Properties.

Yuan Yan et al.

Scientific reports, 5, 16715-16715 (2015-11-20)

In this work, a hierarchical DNA-directed self-assembly strategy to construct structure-controlled Au nanoassemblies (NAs) has been demonstrated by conjugating Au nanoparticles (NPs) with internal-modified dithiol single-strand DNA (ssDNA) (Au-B-A or A-B-Au-B-A). It is found that the dithiol-ssDNA-modified Au NPs and

Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response.

M Ursula Norman et al.

The American journal of pathology, 172(6), 1638-1649 (2008-05-10)

The role that mast cells play during contact hypersensitivity (CS) response is unclear because some studies have shown that mast cell-deficient mice have relatively intact CS responses whereas others have shown opposing results. Mast cells secrete a wide range of

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Global Trade Item Number

SKU	GTIN
G5630-100MG	04061832777542
83697-250MG	04061832533339
83697-1G	04061835079940

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