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Merck
CN

83870

D-Ribose 5-phosphate barium salt hexahydrate

≥99.0% (TLC)

Synonym(s):

R-5-P-Ba

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About This Item

Empirical Formula (Hill Notation):
C5H9BaO8P · 6H2O
CAS Number:
Molecular Weight:
473.51
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
239-750-0
Beilstein/REAXYS Number:
3781061
MDL number:
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Product Name

D-Ribose 5-phosphate barium salt hexahydrate, ≥99.0% (TLC)

InChI key

WUZJSCGFQURQNK-BJLVBTRRSA-L

InChI

1S/C5H11O8P.Ba.6H2O/c6-1-3(7)5(9)4(8)2-13-14(10,11)12;;;;;;;/h1,3-5,7-9H,2H2,(H2,10,11,12);;6*1H2/q;+2;;;;;;/p-2/t3-,4+,5-;;;;;;;/m0......./s1

SMILES string

[Ba++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]C(=O)[C@H](O)[C@H](O)[C@H](O)COP([O-])([O-])=O

assay

≥99.0% (TLC)

form

powder

optical activity

[α]20/D +12±2°, c = 1% in 0.2 M HCl

storage temp.

2-8°C

Quality Level

Application

D-Ribose 5-phosphate is used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) and phosphopentomutase(s). Ribose 5-phosphate is used to study the processes and effects of glycation in vivo and in vitro.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Michelle F Clasquin et al.
Cell, 145(6), 969-980 (2011-06-15)
Glucose is catabolized in yeast via two fundamental routes, glycolysis and the oxidative pentose phosphate pathway, which produces NADPH and the essential nucleotide component ribose-5-phosphate. Here, we describe riboneogenesis, a thermodynamically driven pathway that converts glycolytic intermediates into ribose-5-phosphate without
Rebecca A Gersten et al.
Carbohydrate research, 345(17), 2499-2506 (2010-10-12)
Ribose 5-phosphate (R5P) is a sugar known to undergo the Maillard reaction (glycation) at a rapid rate. In a reaction with the lysines of bovine heart cytochrome c, R5P generates superoxide (O2-) that subsequently reduces ferri-cytochrome c to ferro-cytochrome c.
Timothy D Panosian et al.
The Journal of biological chemistry, 286(10), 8043-8054 (2011-01-05)
Bacterial phosphopentomutases (PPMs) are alkaline phosphatase superfamily members that interconvert α-D-ribose 5-phosphate (ribose 5-phosphate) and α-D-ribose 1-phosphate (ribose 1-phosphate). We investigated the reaction mechanism of Bacillus cereus PPM using a combination of structural and biochemical studies. Four high resolution crystal
T M Iverson et al.
Biochemistry, 51(9), 1964-1975 (2012-02-15)
Prokaryotic phosphopentomutases (PPMs) are di-Mn(2+) enzymes that catalyze the interconversion of α-D-ribose 5-phosphate and α-D-ribose 1-phosphate at an active site located between two independently folded domains. These prokaryotic PPMs belong to the alkaline phosphatase superfamily, but previous studies of Bacillus
Claudia Vanesa Piattoni et al.
Plant physiology, 156(3), 1337-1350 (2011-05-07)
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase (np-Ga3PDHase) is a cytosolic unconventional glycolytic enzyme of plant cells regulated by phosphorylation in heterotrophic tissues. After interaction with 14-3-3 proteins, the phosphorylated enzyme becomes less active and more sensitive to regulation by adenylates and inorganic pyrophosphate.

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