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Merck
CN

84110

Sucrose monolaurate

BioXtra, ≥97.0% (TLC)

Synonym(s):

n-Dodecanoylsucrose, Lauric acid sucrose ester, Sucrose monododecanoate

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About This Item

Empirical Formula (Hill Notation):
C24H44O12
Molecular Weight:
524.60
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57652988
EC Number:
246-873-3
Beilstein/REAXYS Number:
65819
MDL number:
MFCD00077947

Key Documents

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Product Name

Sucrose monolaurate, BioXtra, ≥97.0% (TLC)

InChI key

KGUHOFWIXKIURA-VQXBOQCVSA-N

InChI

1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1

SMILES string

CCCCCCCCCCCC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

description

non-ionic

product line

BioXtra

assay

≥97.0% (TLC)

form

powder

mol wt

524.60 g/mol

impurities

≤3% water

CMC

0.3

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

storage temp.

2-8°C

Quality Level

100

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Application

Sucrose monolaurate has been used as an antimicrobial agent. It has also been used as a constituent of lysis buffer to homogenize placental tissues for determining serine palmitoyltransferase (SPT) activity.

General description

Sucrose monolaurate is a non-ionic detergent and a carbohydrate fatty acid monoester. It is generally used for the solubilization of membrane proteins.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9371
BCCM8605
BCCM5973
BCCK2131
BCCH6351

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Detergents for extraction of visual pigments: types, solubilization, and stability.
S L Fong et al.
Methods in enzymology, 81, 133-140 (1982-01-01)
Prediction of Listeria monocytogenes ATCC 7644 growth on fresh-cut produce treated with bacteriophage and sucrose monolaurate by using artificial neural network
Oladunjoye A, et al.
LWT--Food Science and Technology, 76, 9-17 (2017)
Christopher Rupp et al.
International journal of pharmaceutics, 395(1-2), 272-280 (2010-06-29)
A remarkable part of newly developed active pharmaceutical ingredients is rejected in early phase development and will never find a way to a patient because of poor water solubility which is often paired with poor bioavailability. Considering such arising solubility
Angéla Szuts et al.
International journal of pharmaceutics, 410(1-2), 107-110 (2011-03-23)
This study focused on an investigation of the applicability of sucrose laurate as surfactant in solid dispersions. Although this surfactant has a US Drug Master File, it has not been used so far in internal pharmaceutical products. High drug-loaded solid
Non-reducing trisaccharide fatty acid monoesters: novel detergents in membrane biochemistry
Perez-Victoria I, et al.
Biochimica et Biophysica Acta - Biomembranes, 1808(3), 717-726 (2011)
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