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87787

6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride

Name: 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7<I>H</I>)-one hydrochloride
Brand: SIGMA

suitable for chemiluminescence, ≥98.0% (HPLC)

Synonym(s):

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride, Cypridina Luciferin methoxy-analogue, MCLA

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₃N₃O₂ · HCl

CAS Number:

128322-44-1

Molecular Weight:

291.73

UNSPSC Code:

12352200

NACRES:

NA.32

PubChem Substance ID:

57653269

MDL number:

MFCD00144728

Beilstein/REAXYS Number:

5838857

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Properties

description

luminescence test: Em_max465 nm, 0.1 M Tris pH 8.5; after addition of H₂O₂ (Chemiluminescence: in 0.1 M Tris pH 8.5; after addition of H₂O₂)

assay

≥98.0% (HPLC)

form

powder

solubility

DMSO: soluble, H₂O: soluble

suitability

suitable for chemiluminescence

SMILES string

Cl[H].COc1ccc(cc1)C2=CN3C(=O)C(C)=NC3=CN2

InChI

1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,15H,1-2H3;1H

InChI key

KGMPQNFFCUDXSO-UHFFFAOYSA-N

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Generation of chemiluminescence by reaction with super oxide O₂^– or singlet oxygen. Used in research of leucocyte function.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation.

Yasuhiro Kambayashi et al.

Journal of clinical biochemistry and nutrition, 41(1), 68-75 (2008-04-09)

We have proposed that diacylglycerol hydroperoxide-induced unregulated signal transduction causes oxidative stress-related diseases. In this study, we investigated which molecular species of diacylglycerol hydroperoxide activated human peripheral neutrophils. All diacylglycerol hydroperoxides, diacylglycerol hydroxides, and diacyglycerols tested in the present study

The first observation of O2- generation in in situ lungs of rats treated with drugs to induce experimental acute respiratory distress syndrome.

A Takahashi et al.

FEBS letters, 261(2), 369-372 (1990-02-26)

To investigate O2- generation in in situ lungs of rats treated with drugs to induce experimental acute respiratory distress syndrome, phorbol myristate acetate (PMA) or endotoxin were injected into rats, who had been continuously infused with 2(methyl-6-[p-methoxyphenyl]-3,7-dihydroimidazo[1,2-alpha]pyraz in-3-one (MCLA) and

Sodium Lauryl Sulfate Stimulates the Generation of Reactive Oxygen Species through Interactions with Cell Membranes.

Taeko Mizutani et al.

Journal of oleo science, 65(12), 993-1001 (2016-11-11)

Sodium lauryl sulfate (SLS), a representative anionic surfactant, is well-known to induce rough skin following single or multiple topical applications. The mechanism by which SLS induces rough skin is thought to result from the disruption of skin moisture function consisting

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Global Trade Item Number

SKU	GTIN
87787-10MG-F	04061833278383