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Merck
CN

90718

Fluorescein isothiocyanate–dextran

average Mw 70,000

Synonym(s):

FITC–Dextran 70, FITC–Dextran

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.32
MDL number:
Technical Service
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biological source

synthetic

Quality Segment

conjugate

FITC conjugate

form

powder or crystals

mol wt

average Mw 70,000

extent of labeling

0.001-0.020 mol/mol FITC glucose

fluorescence

λex 493 nm; λem 520 nm±5 nm in 0.1 M Tris pH 8.0

application(s)

cell analysis

General description

Fluorescein isothiocyanate–dextran is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. Fluorescein isothiocyanate–dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform., however, it dissolves in DMSO, formamide, and a few other polar organic solvents.

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
Fluorescein isothiocyanate–dextran has an application of cell analysis, Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. FITC-dextrans are primary source of studying permeability and transport in cells and tissues and can also be a tool for permeability studies of other materials.


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Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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