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90C2

Leukocyte Naphthol AS-D Chloroacetate (Specific Esterase) Kit

Synonym(s):

Leder Stain

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About This Item

NACRES:
NA.47
UNSPSC Code:
12352106
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description

Select reagents packaged in gelatin capsules

Quality Level

500

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

dilution

(for histology)

application(s)

hematology
histology

shipped in

wet ice

storage temp.

2-8°C

Application

Esterases are ubiquitous in nature and encompass a series of different enzymes acting upon select substrates. With the 90C2 kit, Naphthol AS-D Chloroacetate is enzymatically hydrolyzed by "specific esterase, " liberating a free naphthol compound. This then couples with a diazonium salt, forming highly colored deposits at sites of enzyme activity. This enzyme is usually considered specific for cells of granulocytic lineage. May be used to detect neutrophils in peripheral blood, bone marrow or tissue sections which have been paraffin embedded.

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Kit Components Only

Product No.
Description
  • Dimethyl formamide (9010) 25 mL
  • Fast Corinth V Salt (9015) 10 capsules

Kit Components Also Available Separately

Product No.
Description
SDS & Pricing
  • 2852
    Acid Hematoxylin Solution 100 mL
    SDS
  • 905
    Naphthol AS-D Chloroacetate 10 x 20
    SDS
  • 903C
    TRIZMAL™ 6.3 Buffer Concentrate, pH 6.3(concentrate), 0.2 M 50 mL
    SDS

signalword

Danger

supp_hazards

EUH044

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

target_organs

Central nervous system

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - STOT RE 2 Oral

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
SLBT1859
SLBQ8658V
SLBL7093V
SLBL0288
SLBL0289

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Chengjie Ma et al.
Molecular medicine reports, 22(1), 483-493 (2020-04-23)
Inactivation of the Hippo pathway protects the myocardium from cardiac ischemic injury. MicroRNAs (miRs) have been reported to play pivotal roles in the progression of myocardial infarction (MI). The present study examined whether miR‑93 could promote angiogenesis and attenuate remodeling
Feng Dong et al.
Circulation research, 106(3), 601-610 (2009-12-26)
Hypoxia inducible factor (HIF)-1alpha is a transcription factor stabilized by hypoxia. It regulates cytokines involved in the inflammatory response after ischemia and affects white blood cell (WBCs) function. The effect of HIF-1alpha on WBC function and inflammation following myocardial infarction
John Zagorski et al.
Journal of immunology (Baltimore, Md. : 1950), 179(11), 7820-7826 (2007-11-21)
Right ventricular (RV) dysfunction is a strong risk factor for poor clinical outcome following pulmonary embolism (PE), the third most prevalent cardiovascular disease. Previous studies in our laboratory demonstrated that RV failure during PE is mediated, in part, by neutrophil-dependant
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Global Trade Item Number

SKUGTIN
90C2-1KT04061833647806