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Merck
CN

93140

2,3,5-Triphenyltetrazolium chloride

≥99.0% (AT)

Synonym(s):

TPTZ, TTZ, Tetrazolium Red

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About This Item

Empirical Formula (Hill Notation):
C19H15ClN4
CAS Number:
298-96-4
Molecular Weight:
334.80
EC Number:
206-071-6
UNSPSC Code:
12171500
PubChem Substance ID:
329770208
Beilstein/REAXYS Number:
3923356
MDL number:
MFCD00011963

Key Documents

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Product Name

2,3,5-Triphenyltetrazolium chloride, ≥99.0% (AT)

InChI key

PKDBCJSWQUOKDO-UHFFFAOYSA-M

InChI

1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1

SMILES string

[Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4

assay

≥99.0% (AT)

form

powder

solubility

methanol: 1 g/10 mL

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Other Notes

Review: Tetrazolium salts and formazans

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBQ1915V
BCBP9555V
BCBP3272V
BCBN2351V
BCBN0286V

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Xiao Zhang et al.
Neurochemical research, 39(7), 1363-1373 (2014-05-06)
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We previously reported the promising effect of dioscin against hepatic ischemia/reperfusion (I/R) injury, but its effect on cerebral I/R injury remains unknown. In this work, an in vitro oxygen-glucose deprivation and reoxygenation (OGD/R) model and an in vivo middle cerebral
Y Yang et al.
NMR in biomedicine, 25(1), 177-188 (2011-10-01)
The aim of the study was the testing of sustained intrapericardial delivery of vascular growth factors (GFs) from alginate beads on cryoinjury size and perfusion. In domestic pigs (15-20 kg, n = 21), the left ventricular (LV) anterolateral wall of
Liyan Ping et al.
PloS one, 7(6), e38427-e38427 (2012-06-08)
Tetrazolium salts are widely used in biology as indicators of metabolic activity - hence termed vital dyes - but their reduction site is still debated despite decades of intensive research. The prototype, 2,3,5- triphenyl tetrazolium chloride, which was first synthesized
Joana Arbeloa et al.
Neurobiology of disease, 45(3), 954-961 (2011-12-22)
Overactivation of subtype P2X7 receptors can induce excitotoxic neuronal death by calcium (Ca(2+)) overload. In this study, we characterize the functional properties of P2X7 receptors using electrophysiology and Ca(2+) monitoring in primary cortical neuron cultures and in brain slices. Both
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