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Merck
CN

95255

D-α-Tocopherol succinate

BioXtra, ≥98.0% (HPLC)

Synonym(s):

Vitamin E succinate

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About This Item

Empirical Formula (Hill Notation):
C33H54O5
CAS Number:
4345-03-3
Molecular Weight:
530.78
UNSPSC Code:
12352211
NACRES:
NA.79
PubChem Substance ID:
57653662
EC Number:
224-403-8
Beilstein/REAXYS Number:
4038233
MDL number:
MFCD00072055

Key Documents

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Product Name

D-α-Tocopherol succinate, BioXtra, ≥98.0% (HPLC)

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChI key

IELOKBJPULMYRW-NJQVLOCASA-N

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

product line

BioXtra

assay

≥98.0% (HPLC)

form

powder

color

white to faint yellow

storage temp.

2-8°C

Quality Level

100

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Biochem/physiol Actions

Tocopherol exhibits antioxidant property by protecting the cells and membranes from oxidative stress. In plants, high levels of α-tocopherol leads to plant stress tolerance whereas low levels is associated with oxidative stress. In humans, tocopherol prevents cancer, premature aging, atherosclerosis, arthritis caused due to free radicals. Vitamin E succinate (VES) is an anti-tumor analog of vitamin E.

General description

Tocopherol is a lipid soluble vitamin E. It is present in food sources, such as soybean, almond oil, sunflower oil. Tocopherol has four isoforms in plants, which are α, β, γ and δ. It is composed of a chromanol ring with varied position of methyl group. D-αTocopherol succinate is also known as vitamin E succinate (VES).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9627
BCCD7636
BCBM3244V
BCBL8476V
BCBK9311V

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Implications of light energy on food quality and packaging selection
Advances in Food and Nutrition Research, 67, 25-73 (2012)
Tocopherol succinate: a promising radiation countermeasure.
Singh VK, Brown DS, Kao TC.
International Journal of Immunopharmacology, 9, 1423-1430 (2009)
Specialty oils: functional and nutraceutical properties
Functional Dietary Lipids, 67, 69-101 (2016)
Tocopherol succinate: modulation of antioxidant enzymes and oncogene expression, and hematopoietic recovery.
Singh VK, Parekh VI, et al.
Int. J. Radiation Oncology Biol. Phys., 79, 571-578 (2011)
Xuhui Zhang et al.
The British journal of nutrition, 104(12), 1796-1805 (2010-09-03)
The anti-inflammatory effects of two esters of a-tocopherol (α-TOH), all-rac-α-TOH acetate (DL-α-TOA) and RRR-α-TOH succinate (D-α-TOS), on broilers repeatedly challenged with lipopolysaccharide (LPS) were investigated. Three hundred and twenty 1-d-old broiler chicks were allotted into four treatment groups and fed
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