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Merck
CN

96924

2,2,2-Trifluoroethanol

BioUltra, Molecular Biology, ≥99.0% (GC)

Synonym(s):

Trifluoroethyl alcohol

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About This Item

Linear Formula:
CF3CH2OH
CAS Number:
Molecular Weight:
100.04
UNSPSC Code:
12352200
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-913-6
Beilstein/REAXYS Number:
1733203
MDL number:
Assay:
≥99.0% (GC)
Grade:
Molecular Biology
Technique(s):
GC/GC: suitable
Bp:
77-80 °C (lit.)
Vapor pressure:
70 mmHg ( 25 °C)
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grade

Molecular Biology

vapor density

3.5 (vs air)

vapor pressure

70 mmHg ( 25 °C)

product line

BioUltra

assay

≥99.0% (GC)

form

liquid

autoignition temp.

~896 °F

expl. lim.

42 %

technique(s)

GC/GC: suitable

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

refractive index

n20/D 1.3 (lit.)

bp

77-80 °C (lit.)

mp

−44 °C (lit.)

density

1.373 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.02 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.1 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.1 mg/kg, Na: ≤1 mg/kg, Ni: ≤0.02 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

λ

neat

SMILES string

OCC(F)(F)F

UV absorption

λ: 260 nm Amax: ≤0.03, λ: 280 nm Amax: ≤0.02

application(s)

sample preparation

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

InChI key

RHQDFWAXVIIEBN-UHFFFAOYSA-N

Application

2,2,2-Trifluoroethanol (Trifluoroethyl alcohol, TFE) is used to study the conformational states of proteins and the folding refolding processes of proteins.

Other Notes

Solvent used for sample preparation in electrophoresis


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Blood

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

86.0 °F - closed cup

flash_point_c

30 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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K Shiraki et al.
Journal of molecular biology, 245(2), 180-194 (1995-01-13)
Trifluoroethanol (TFE) is known to stabilize the alpha-helical structure in proteins and their fragments. However, the relationship between the TFE-induced structures and the native structure is not clear. Here we show that beta-lactoglobulin, which consists predominantly of beta-sheets, exhibited a
T Rabilloud et al.
Electrophoresis, 19(6), 1006-1014 (1998-06-25)
Owing to the complexity of higher eukaryotic cells, characterization of a complete proteome is likely to be difficult to achieve. However, advantage can be taken of the cell compartmentalization to build organelle proteomes, which can moreover be viewed as specialized
Na Zhang et al.
Biomaterials science, 8(22), 6286-6300 (2020-10-07)
The regeneration of injured neurons over long injury distances remains suboptimal. In order to successfully stimulate nerve regrowth, potent biomolecules are necessary. Furthermore, reproducible and translatable methods to test the potency of candidate drugs for enhancing nerve regeneration over long



Global Trade Item Number

SKUGTIN
96924-50ML-F04061833324691
96924-250ML-F04061833324684