L8643
Lipopolysaccharides from Pseudomonas aeruginosa 10
purified by gel-filtration chromatography
Synonym(s):
LPS
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About This Item
biological source
Pseudomonas aeruginosa (10)
Quality Level
form
lyophilized powder
purified by
gel-filtration chromatography
impurities
<3% Protein (Lowry)
color
white to faint yellow
solubility
water: 4.90-5.10 mg/mL, cloudy to hazy, colorless to faintly yellow
storage temp.
2-8°C
Application
Lipopolysaccharides from Pseudomonas aeruginosa 10 has been used as an inflammatory mediator in cells.
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Other Notes
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
Austin Boucher et al.
Journal of immunology (Baltimore, Md. : 1950), 206(3), 540-553 (2020-12-18)
Macrophages are critical for regulating inflammatory responses. Environmental signals polarize macrophages to either a proinflammatory (M1) state or an anti-inflammatory (M2) state. We observed that the microRNA (miRNA) cluster mirn23a, coding for miRs-23a, -27a, and -24-2, regulates mouse macrophage polarization.
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice.
Bruscia EM
American Journal of Respiratory Cell and Molecular Biology, 40, 295-295 (2009)
Sandra Chang et al.
PloS one, 10(7), e0131810-e0131810 (2015-07-07)
Oxidant production from DUOX1 has been proposed to lead to neutrophil recruitment into the airways when lung homeostasis is compromised. The objective of this study was to determine whether DUOX-derived hydrogen peroxide is required for LPS-induced neutrophil recruitment, using a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L8643-5MG | 04061833275320 |
| L8643-10MG | 04061833275313 |