Skip to Content
Merck
CN

Key Documents

View All Documentation

A0184

Amyloid β-Protein Fragment 1-28

≥97% (HPLC)

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C145H209N41O46
CAS Number:
106686-61-7
Molecular Weight:
3262.46
UNSPSC Code:
12352200
MDL number:
MFCD00133074
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥97% (HPLC)

UniProt accession no.

P05067

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc5ccccc5)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H](Cc7ccccc7)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O

Gene Information

human ... APP(351)

Biochem/physiol Actions

β-Amyloid peptide that forms fibrils in vitro that have the same structure and antigenicity as those found in Alzheimer′s patients.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
114K09151
110K1456
103K12601
066K1792
056K15251

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J J Miguel-Hidalgo et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 8(3), 203-208 (1998-08-26)
We assessed the neuroprotective capabilities of S12024 (R,S 1-methyl 8-(2-morpholinylmethoxy)-1,2,3,4-tetrahydroquinoleine methane sulphonate) in a model of neuronal degeneration in the dentate gyrus of the rat hippocampus. Specific degeneration of a large part of neurons in the lateral blade of the
X A Alvarez et al.
Methods and findings in experimental and clinical pharmacology, 19(7), 471-479 (1997-12-31)
beta-amyloid (beta A) deposition is a key event in the etiopathogenesis of Alzheimer's disease (AD), contributing to neuronal degeneration and cognitive impairment in AD patients. Both neurotrophic and neurotoxic actions of beta A have been demonstrated in experimental conditions. In
T G Fletcher et al.
Protein science : a publication of the Protein Society, 6(3), 666-675 (1997-03-01)
The neurotoxicity of beta-amyloid protein (beta AP) fragments may be a result of their solution conformation, which is very sensitive to solution conditions. In this work we describe NMR and CD studies of the conformation of beta AP(12-28) in lipid
View All Related Papers