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Merck
CN

A0433

Anti-Albumin antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti Albumin Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
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Product Name

Anti-Albumin antibody produced in rabbit, IgG fraction of antiserum

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

mol wt

antigen 65 kDa

species reactivity

human

technique(s)

indirect ELISA: 1:25,000
quantitative precipitin assay: 4.0-10.0 mg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ALB(213)

Application

Anti-Albumin antibody produced in rabbit has been used in:
  • immunocytochemistry
  • immunoassay of amino-terminal fragments(ATF)-human serum albumin (HSA)
  • canstatin (Can) - human serum albumin (HSA)
  • enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

Rabbit polyclonal anti-Albumin antibody reacts with human serum and human albumin.
Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease. High levels of albumin are associated with dehydration. Albumin turnover is seen in infants with iron deficiency anemia. Advanced liver disease is associated with oxidative damage of albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Albumin is the most abundant plasma protein in humans.
Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin.

Immunogen

purified human albumin

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment
Magnon C, et al.
Gene Therapy, 15(21), 1436-1436 (2008)
Xun Li et al.
Molecular cancer, 18(1), 99-99 (2019-05-28)
Our previous report demonstrated that genetic ablation of miR-301a reduces Kras-driven lung tumorigenesis in mice. However, the impact of miR-301a on host anti-tumor immunity remains unexplored. Here we assessed the underlying molecular mechanisms of miR-301a in the tumor microenvironment. The
A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer
Frau E, et al.
Cancer Gene Therapy, 14(3), 251-251 (2007)
Siti S Abdullah-Soheimi et al.
Proteome science, 8, 58-58 (2010-11-19)
Diagnosis of ovarian carcinoma is in urgent need for new complementary biomarkers for early stage detection. Proteins that are aberrantly excreted in the urine of cancer patients are excellent biomarker candidates for development of new noninvasive protocol for early diagnosis
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed
McLean AB, et al.
Stem Cells, 25(1), 29-38 (2007)

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