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A0542

Amprolium hydrochloride

Name: Amprolium hydrochloride
Brand: SIGMA

Synonym(s):

1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride

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About This Item

Linear Formula:

C₁₄H₁₉N₄Cl · HCl

CAS Number:

137-88-2

Molecular Weight:

315.24

UNSPSC Code:

12161900

NACRES:

NA.25

PubChem Substance ID:

24890432

EC Number:

205-307-5

Beilstein/REAXYS Number:

4118699

MDL number:

MFCD00078831

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description

cationic

Quality Level

200

assay

≥98.0% (TLC)

form

powder

mol wt

315.24 g/mol

technique(s)

cell culture | mammalian: suitable, microbiological culture: suitable

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

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Related Categories

Biochemicals

Detergents - Anionic, Cationic, Zwitterionic, Anti-foaming

Chemistry & Biochemicals

pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000521632

0000521633

0000488579

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Efficacy of amprolium for the treatment of pathogenic Eimeria species in Boer goat kids.

Gabrielle Young et al.

Veterinary parasitology, 178(3-4), 346-349 (2011-02-22)

This study evaluated the efficacy of two different doses of amprolium in goats heavily infected with pathogenic Eimeria species. Forty Boer goat kids ranging from 3 to 5 months of age with naturally occurring coccidiosis were randomly divided into 2

Anticoccidial effects of Ageratum conyzoides.

N E Nweze et al.

Journal of ethnopharmacology, 122(1), 6-9 (2008-12-17)

Ageratum conyzoides (Asteraceae) is folklorically used to treat diseases associated with bleeding. A study was conducted to determine the efficacy of Ageratum conyzoides in treating caecal coccidiosis of broilers. Acute toxicity test was done using thirty 28 days old broiler

Thiamine is a substrate of organic cation transporters in Caco-2 cells.

Clara Lemos et al.

European journal of pharmacology, 682(1-3), 37-42 (2012-03-06)

The aim of this study was to characterize the intestinal absorption of thiamine, by investigating the hypothesis of an involvement of Organic Cation Transporter (OCT) family members in this process. [(3)H]-T(+) uptake was found to be: 1) time-dependent, 2) Na(+)-

Comparative therapeutic effect of toltrazuril, sulphadimidine and amprolium on Eimeria bovis and Eimeria zuernii given at different times following infection in buffalo calves (Bubalus bubalis).

Mohamed M Ghanem et al.

Preventive veterinary medicine, 84(1-2), 161-170 (2008-02-12)

We compared the therapeutic effect of three anticoccidial drugs (toltrazuril, sulphadimidine and amprolium) in buffalo (Bubalus bubalis) calves experimentally infected with Eimeria bovis (E. bovis) and E. zuernii oocysts (3 x 104oocyst/calf). Buffalo calves (1.5-4 month old, 70-kg body weight)

Acetyl-CoA metabolism in amprolium-evoked thiamine pyrophosphate deficits in cholinergic SN56 neuroblastoma cells.

D Bizon-Zygmańska et al.

Neurochemistry international, 59(2), 208-216 (2011-06-16)

Inhibition of pyruvate (PDHC) and ketoglutarate (KDHC) dehydrogenase complexes induced by thiamine pyrophosphate deficits is known cause of disturbances of cholinergic transmission in the brain, yielding clinical symptoms of cognitive, vegetative and motor deficits. However, particular alterations in distribution of

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Global Trade Item Number

SKU	GTIN
A0542-25G	04061833334072

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