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Merck
CN

A0542

Amprolium hydrochloride

Synonym(s):

1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride

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About This Item

Linear Formula:
C14H19N4Cl · HCl
CAS Number:
137-88-2
Molecular Weight:
315.24
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24890432
EC Number:
205-307-5
Beilstein/REAXYS Number:
4118699
MDL number:
MFCD00078831

Key Documents

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InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

description

cationic

assay

≥98.0% (TLC)

form

powder

mol wt

315.24 g/mol

technique(s)

cell culture | mammalian: suitable
microbiological culture: suitable

Quality Level

200

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000521632
0000521632
0000521633
0000521633
0000488579

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X Wang et al.
Neuroscience, 144(3), 1045-1056 (2006-12-02)
Thiamine (vitamin B1) deficiency (TD) causes region selective neuronal loss in the brain; it has been used to model neurodegeneration that accompanies mild impairment of oxidative metabolism. The mechanisms for TD-induced neurodegeneration remain incompletely elucidated. Inhibition of protein glycosylation, perturbation
Anna Martínez-Villalba et al.
Journal of chromatography. A, 1217(37), 5802-5807 (2010-08-11)
We present a fast liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the analysis of the coccidiostat amprolium in food samples. Tandem mass spectrometry in a triple quadrupole was used for quantitative purposes, and the information from multiple-stage mass spectrometry in
N Furusawa
Journal of chromatographic science, 40(6), 355-358 (2002-07-26)
A simplified determining method for the routine monitoring of residual amprolium in edible chicken tissues (muscle and liver) is developed using a high-performance liquid chromatographic (HPLC) method with a photodiode-array detector after sample cleanup by an Ultrafree-MC/PL centrifugal ultrafiltration unit.
E Karagouni et al.
International journal of immunopathology and pharmacology, 18(1), 121-132 (2005-02-09)
The aim of the present study was to investigate the impact of a successful anti-myxosporean medication on the innate immune system of fish intensively cultured in the Mediterranean basin. For this purpose, juvenile and adult gilthead seabream (S. aurata L.)
Clara Lemos et al.
European journal of pharmacology, 682(1-3), 37-42 (2012-03-06)
The aim of this study was to characterize the intestinal absorption of thiamine, by investigating the hypothesis of an involvement of Organic Cation Transporter (OCT) family members in this process. [(3)H]-T(+) uptake was found to be: 1) time-dependent, 2) Na(+)-
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